The poly(A) signal, without the assistance of any downstream element, directs RNA polymerase II to pause in vivo and then to release stochastically from the template (Q46370210)

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English	The poly(A) signal, without the assistance of any downstream element, directs RNA polymerase II to pause in vivo and then to release stochastically from the template	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/12196547

The poly(A) signal, without the assistance of any downstream element, directs RNA polymerase II to pause in vivo and then to release stochastically from the template (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/12196547

author name string

Ian J Orozco

1

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/12196547

Steven J Kim

2

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/12196547

Harold G Martinson

3

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/12196547

language of work or name

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publication date

23 August 2002

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/12196547

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/12196547

277

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/12196547

45

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/12196547

42899-42911

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/12196547

P-TEFb, a cyclin-dependent kinase controlling elongation by RNA polymerase II

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Three functional classes of transcriptional activation domain

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Transcriptional pause, arrest and termination sites for RNA polymerase II in mammalian N- and c-myc genes

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Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation

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Integrating mRNA processing with transcription

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How RNA polymerase II terminates transcription in higher eukaryotes

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21 January 2018

Poly(A)-driven and poly(A)-assisted termination: two different modes of poly(A)-dependent transcription termination

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Mechanism of poly(A) signal transduction to RNA polymerase II in vitro

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DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation

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Distinct properties of c-myc transcriptional elongation are revealed in Xenopus oocytes and mammalian cells and by template titration, 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB), and promoter mutagenesis

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A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene

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EM visualization of transcription by RNA polymerase II: downstream termination requires a poly(A) signal but not transcript cleavage.

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Characterization of the mouse beta maj globin transcription termination region: a spacing sequence is required between the poly(A) signal sequence and multiple downstream termination elements

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An apparent pause site in the transcription unit of the rabbit α-globin gene

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An RNA polymerase pause site is associated with the immunoglobulin mus poly(A) site

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Transcriptional termination signals for RNA polymerase II in fission yeast

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Transcription and polyadenylation in a short human intergenic region.

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Nascent transcription from the nmt1 and nmt2 genes of Schizosaccharomyces pombe overlaps neighbouring genes.

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Multiple factors prevent transcriptional interference at the yeast ARO4-HIS7 locus

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MAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and termination

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RNA polymerase II transcription termination is mediated specifically by protein binding to a CCAAT box sequence

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Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase II

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Balancing transcriptional interference and initiation on the GAL7 promoter of Saccharomyces cerevisiae

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Activation of Rho-dependent transcription termination by NusG. Dependence on terminator location and acceleration of RNA release

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Rho-dependent termination within the trp t' terminator. I. Effects of rho loading and template sequence

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Transcription termination at the chicken beta H-globin gene

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The RNA polymerase II molecule at the 5' end of the uninduced hsp70 gene of D. melanogaster is transcriptionally engaged.

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The block to transcriptional elongation within the human c-myc gene is determined in the promoter-proximal region

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Functionally significant secondary structure of the simian virus 40 late polyadenylation signal

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Transcription of eukaryotic protein-coding genes

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Interactions between fission yeast mRNA capping enzymes and elongation factor Spt5.

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Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster

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High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation

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Efficiency of utilization of the simian virus 40 late polyadenylation site: effects of upstream sequences

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The regulated production of mu m and mu s mRNA is dependent on the relative efficiencies of mu s poly(A) site usage and the c mu 4-to-M1 splice

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Co-transcriptional commitment to alternative splice site selection.

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Specific transcriptional pausing activates polyadenylation in a coupled in vitro system

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RNA polymerase II is an essential mRNA polyadenylation factor

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Single-molecule study of transcriptional pausing and arrest by E. coli RNA polymerase

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A functional mRNA polyadenylation signal is required for transcription termination by RNA polymerase II

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Termination of transcription in the mouse alpha-amylase gene Amy-2a occurs at multiple sites downstream of the polyadenylation site

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Transcription by RNA polymerase II induces changes of DNA topology in yeast

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Saccharomyces cerevisiae mRNA 3′ end forming signals are also involved in transcription termination

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On the activity of RNA polymerase B in lysates from Ehrlich ascites cells

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Activation of pausing RNA polymerases by nuclear run-on experiments

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Identifiers

10.1074/JBC.M207415200

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/12196547

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 December 2017

http://europepmc.org/abstract/MED/12196547

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