A redox-sensitive pathway mediates oxidized LDL-induced downregulation of insulin-like growth factor-1 receptor (Q46417743)

22 December 2017

title

A redox-sensitive pathway mediates oxidized LDL-induced downregulation of insulin-like growth factor-1 receptor (English)

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22 December 2017

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22 December 2017

Patrice Delafontaine

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22 December 2017

author name string

Yusuke Higashi

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22 December 2017

Tao Peng

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22 December 2017

Jie Du

3

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22 December 2017

Yangxin Li

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22 December 2017

Hiroyuki Itabe

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22 December 2017

Sampath Parthasarathy

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22 December 2017

publication date

1 April 2005

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22 December 2017

Journal of Lipid Research

published in

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22 December 2017

volume

46

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22 December 2017

issue

6

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22 December 2017

page(s)

1266-1277

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22 December 2017

Atherosclerotic plaque rupture--pathologic basis of plaque stability and instability

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Oxidized low-density lipoprotein is associated with apoptosis of vascular smooth muscle cells in human atherosclerotic plaques

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Mildly oxidized low density lipoprotein activates multiple apoptotic signaling pathways in human coronary cells

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Oxidized low density lipoprotein induces apoptosis via generation of reactive oxygen species in vascular smooth muscle cells

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Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells

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Insulin-like growth factor-1 receptor activation inhibits oxidized LDL-induced cytochrome C release and apoptosis via the phosphatidylinositol 3 kinase/Akt signaling pathway

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Oxidized phosphatidylcholines that modify proteins. Analysis by monoclonal antibody against oxidized low density lipoprotein

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SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

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PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL

21 January 2018

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Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma

21 January 2018

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Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells

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An extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition

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Class A scavenger receptor up-regulation in smooth muscle cells by oxidized low density lipoprotein. Enhancement by calcium flux and concurrent cyclooxygenase-2 up-regulation

21 January 2018

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Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

21 January 2018

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c-Src induces phosphorylation and translocation of p47phox: role in superoxide generation by angiotensin II in human vascular smooth muscle cells

21 January 2018

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Cloning and sequence analysis of the cDNA for arachidonate 12-lipoxygenase of porcine leukocytes

21 January 2018

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21 January 2018

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21 January 2018

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12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo

21 January 2018

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Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice

21 January 2018

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Decreased Expression of Insulin-like Growth Factor-1 and Apoptosis of Vascular Smooth Muscle Cells in Human Atherosclerotic Plaque

21 January 2018

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Differential effects of low density lipoproteins on IGF-1 and IGF-1R expression in vascular smooth muscle cells

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Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

21 January 2018

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10.1194/JLR.M400478-JLR200

21 January 2018

Identifiers

DOI

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22 December 2017

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22 December 2017