Probing the beta2 adrenoceptor binding site with catechol reveals differences in binding and activation by agonists and partial agonists (Q46427567)

22 December 2017

title

Probing the beta2 adrenoceptor binding site with catechol reveals differences in binding and activation by agonists and partial agonists (English)

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22 December 2017

7

Brian Kobilka

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22 December 2017

6

Tong Sun Kobilka

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22 December 2017

Gayathri Swaminath

1

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22 December 2017

Xavier Deupi

2

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22 December 2017

Tae Weon Lee

3

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22 December 2017

Wen Zhu

4

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22 December 2017

Foon Sun Thian

5

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22 December 2017

language of work or name

English

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publication date

7 April 2005

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22 December 2017

Journal of Biological Chemistry

published in

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22 December 2017

volume

280

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22 December 2017

issue

23

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22 December 2017

page(s)

22165-22171

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22 December 2017

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Functionally different agonists induce distinct conformations in the G protein coupling domain of the beta 2 adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Ligand-selective receptor conformations revisited: the promise and the problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Involvement of Asn-293 in stereospecific agonist recognition and in activation of the beta 2-adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

The forgotten serine. A critical role for Ser-2035.42 in ligand binding to and activation of the beta 2-adrenergic receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Sequential binding of agonists to the beta2 adrenoceptor. Kinetic evidence for intermediate conformational states

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Amino and carboxyl terminal modifications to facilitate the production and purification of a G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Restricting the mobility of Gs alpha: impact on receptor and effector coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

A graph-theory algorithm for rapid protein side-chain prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Modeling of loops in protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Development and testing of a general amber force field

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Raster3D: photorealistic molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Mutation of a single TMVI residue, Phe(282), in the beta(2)-adrenergic receptor results in structurally distinct activated receptor conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Fragment-based lead discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

The neurokinin A receptor activates calcium and cAMP responses through distinct conformational states

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

"Induced-fit" mechanism for catecholamine binding to the beta2-adrenergic receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Synergistic contributions of the functional groups of epinephrine to its affinity and efficacy at the beta2 adrenergic receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Agonist binding: a multistep process

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M502352200

Structural basis of beta-adrenergic receptor function.

21 January 2018

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M502352200

Tyr199 in transmembrane domain 5 of the beta2-adrenergic receptor interacts directly with the pharmacophore of a unique fluorenone-based antagonist

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M502352200

Identifiers

DOI

10.1074/JBC.M502352200

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22 December 2017

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22 December 2017