Characterization of 5,6- and 8,9-epoxyeicosatrienoic acids (5,6- and 8,9-EET) as potent in vivo angiogenic lipids (Q46510528)

22 December 2017

title

Characterization of 5,6- and 8,9-epoxyeicosatrienoic acids (5,6- and 8,9-EET) as potent in vivo angiogenic lipids (English)

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7

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author name string

Ambra Pozzi

1

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Ines Macias-Perez

2

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Tristin Abair

3

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Shouzuo Wei

4

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Yan Su

5

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Roy Zent

6

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Jorge H Capdevila

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language of work or name

English

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publication date

24 May 2005

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Journal of Biological Chemistry

published in

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volume

280

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issue

29

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page(s)

27138-27146

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22 December 2017

Eicosanoid regulation of angiogenesis in tumors

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Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic Acid

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Epoxygenase-driven angiogenesis in human lung microvascular endothelial cells

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Cytochrome P450 2C9-derived epoxyeicosatrienoic acids induce angiogenesis via cross-talk with the epidermal growth factor receptor (EGFR).

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P-450 metabolites of arachidonic acid in the control of cardiovascular function

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The kidney cytochrome P-450 2C23 arachidonic acid epoxygenase is upregulated during dietary salt loading.

21 January 2018

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CYP2C44, a new murine CYP2C that metabolizes arachidonic acid to unique stereospecific products.

21 January 2018

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Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function

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Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform

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Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor.

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Heparin-binding EGF-like growth factor mediates the biological effects of P450 arachidonate epoxygenase metabolites in epithelial cells

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Origin and function of epoxyeicosatrienoic acids in vascular endothelial cells: more than just endothelium-derived hyperpolarizing factor?

21 January 2018

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Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization

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Cytochrome P450 epoxygenases as EDHF synthase(s).

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Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures

21 January 2018

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CARP, a cardiac ankyrin repeat protein, is up-regulated during wound healing and induces angiogenesis in experimental granulation tissue

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Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo.

21 January 2018

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Cytochrome P450 2C is an EDHF synthase in coronary arteries

21 January 2018

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Epoxygenase metabolites contribute to nitric oxide-independent afferent arteriolar vasodilation in response to bradykinin

21 January 2018

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Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids

21 January 2018

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Epoxyeicosatrienoic acids and their sulfonimide derivatives stimulate tyrosine phosphorylation and induce mitogenesis in renal epithelial cells

21 January 2018

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Cytochrome P450 2C9-induced endothelial cell proliferation involves induction of mitogen-activated protein (MAP) kinase phosphatase-1, inhibition of the c-Jun N-terminal kinase, and up-regulation of cyclin D1.

21 January 2018

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11,12-Epoxyeicosatrienoic acid-induced inhibition of FOXO factors promotes endothelial proliferation by down-regulating p27Kip1.

21 January 2018

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Up-regulation of endothelial nitric-oxide synthase by endothelium-derived hyperpolarizing factor involves mitogen-activated protein kinase and protein kinase C signaling pathways.

21 January 2018

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Targeting tumor vasculature with homing peptides from phage display

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21 January 2018

Identifiers

DOI

10.1074/JBC.M501730200

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22 December 2017

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22 December 2017