JAK/STAT signaling by cytokine receptors (Q46606420)

23 December 2017

review article

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title

JAK/STAT signaling by cytokine receptors (English)

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23 December 2017

author name string

Liu KD

series ordinal

1

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23 December 2017

Gaffen SL

series ordinal

2

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23 December 2017

Goldsmith MA

series ordinal

3

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23 December 2017

publication date

1 June 1998

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23 December 2017

Current Opinion in Immunology

published in

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23 December 2017

volume

10

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23 December 2017

issue

3

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23 December 2017

page(s)

271-278

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23 December 2017

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

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Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins

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Interferon-induced nuclear signalling by Jak protein tyrosine kinases

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A Single Phosphotyrosine Residue of Stat91 Required for Gene Activation by Interferon-γ

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Active and inactive protein kinases: structural basis for regulation

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Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation

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Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase

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Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop

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Regulation of interferon-alpha responsiveness by the duration of Janus kinase activity

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Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity

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Direct association with and dephosphorylation of Jak2 kinase by the SH2-domain-containing protein tyrosine phosphatase SHP-1

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Molecular characterization of specific interactions between SHP-2 phosphatase and JAK tyrosine kinases

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7 January 2021

The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase.

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Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway

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Down-regulation of interferon gamma-activated STAT1 by UV light

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A family of cytokine-inducible inhibitors of signalling

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Structure and function of a new STAT-induced STAT inhibitor

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7 January 2021

A new protein containing an SH2 domain that inhibits JAK kinases

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7 January 2021

Specific inhibition of Stat3 signal transduction by PIAS3

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7 January 2021

Defective lymphoid development in mice lacking Jak3

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Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

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7 January 2021

Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3

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Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

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Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

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Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

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Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

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Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans

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Identification of a variable region within the cytoplasmic tail of the IL-2 receptor beta chain that is required for growth signal transduction

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Peripheral expression of Jak3 is required to maintain T lymphocyte function

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7 January 2021

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

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Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

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Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

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Induction by EGF and interferon-gamma of tyrosine phosphorylated DNA binding proteins in mouse liver nuclei.

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The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

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An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor alpha chain induction

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

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Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

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Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

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Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

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Essential role of Stat6 in IL-4 signalling

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Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

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7 January 2021

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

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7 January 2021

Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

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7 January 2021

IL-12-deficient mice are defective but not devoid of type 1 cytokine responses.

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7 January 2021

Constitutively Activated Jak-STAT Pathway in T Cells Transformed with HTLV-I

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7 January 2021

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

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7 January 2021

Jak-STAT signaling induced by the v-abl oncogene

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7 January 2021

Stripe-specific regulation of pair-rule genes by hopscotch, a putative Jak family tyrosine kinase in Drosophila

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7 January 2021

Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects.

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7 January 2021

An amino acid substitution in the Drosophila hopTum-l Jak kinase causes leukemia-like hematopoietic defects.

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7 January 2021

Identification of a Stat gene that functions in Drosophila development

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7 January 2021

Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs

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7 January 2021

A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

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7 January 2021

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

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7 January 2021

Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

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7 January 2021

Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma

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7 January 2021

Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis

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7 January 2021

Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins

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7 January 2021

Cell-free activation of a DNA-binding protein by epidermal growth factor

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7 January 2021

Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor

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7 January 2021

Functional interactions between Stat5 and the glucocorticoid receptor

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7 January 2021

Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300.

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7 January 2021

Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling

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7 January 2021

STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFNAR1 chain of the type I interferon receptor

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7 January 2021

An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT.

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https://api.crossref.org/works/10.1016%2FS0952-7915%2898%2980165-9

7 January 2021

Jak3 is associated with CD40 and is critical for CD40 induction of gene expression in B cells

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7 January 2021

Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling

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7 January 2021

10.1016/S0952-7915(98)80165-9

Identifiers

DOI

1 reference

23 December 2017

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23 December 2017