Comparison of structure and dynamics of micelle-bound human alpha-synuclein and Parkinson disease variants (Q46705919)

24 December 2017

title

Comparison of structure and dynamics of micelle-bound human alpha-synuclein and Parkinson disease variants (English)

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24 December 2017

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2

Ad Bax

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24 December 2017

author name string

Tobias S Ulmer

series ordinal

1

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24 December 2017

language of work or name

English

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publication date

15 September 2005

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24 December 2017

Journal of Biological Chemistry

published in

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24 December 2017

volume

280

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24 December 2017

issue

52

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24 December 2017

page(s)

43179-43187

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24 December 2017

Neurobiology of alpha-synuclein

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Alpha-synuclein: normal function and role in neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Alzheimer's disease and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Alpha-synuclein in Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Alpha synuclein is present in Lewy bodies in sporadic Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

alpha-Synuclein locus triplication causes Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Molecular Pathways of Neurodegeneration in Parkinson's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

A broken alpha -helix in folded alpha -Synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Conformational properties of alpha-synuclein in its free and lipid-associated states

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Structure and dynamics of micelle-bound human alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

alpha-synuclein is phosphorylated by members of the Src family of protein-tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Alpha-synuclein has a high affinity for packing defects in a bilayer membrane: a thermodynamics study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

α-Synuclein Association with Phosphatidylglycerol Probed by Lipid Spin Labels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Human recombinant NACP/alpha-synuclein is aggregated and fibrillated in vitro: relevance for Lewy body disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Exposure to long chain polyunsaturated fatty acids triggers rapid multimerization of synucleins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Lipid droplet binding and oligomerization properties of the Parkinson's disease protein alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Membrane binding and self-association of alpha-synucleins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Mutation E46K increases phospholipid binding and assembly into filaments of human alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

The E46K mutation in alpha-synuclein increases amyloid fibril formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Effects of Parkinson's disease-linked mutations on the structure of lipid-associated alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Defective membrane interactions of familial Parkinson's disease mutant A30P alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Evaluation of backbone proton positions and dynamics in a small protein by liquid crystal NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Amide proton relaxation measurements employing a highly deuterated protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Measurement of Proton, Nitrogen, and Carbonyl Chemical Shielding Anisotropies in a Protein Dissolved in a Dilute Liquid Crystalline Phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Molecular fragment replacement approach to protein structure determination by chemical shift and dipolar homology database mining.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

The Xplor-NIH NMR molecular structure determination package

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

An empirical backbone-backbone hydrogen-bonding potential in proteins and its applications to NMR structure refinement and validation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Sources of and solutions to problems in the refinement of protein NMR structures against torsion angle potentials of mean force.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Determination of the critical micelle concentration of surfactants using the fluorescent probe N-phenyl-1-naphthylamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Chemical shifts in amino acids, peptides, and proteins: from quantum chemistry to drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Structural and dynamic analysis of residual dipolar coupling data for proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Residual dipolar couplings and some specific models for motional averaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Protein backbone dynamics from N-HN dipolar couplings in partially aligned systems: a comparison of motional models in the presence of structural noise

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Experimentally observed conformation-dependent geometry and hidden strain in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Continuum secondary structure captures protein flexibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Geometrical and sequence characteristics of alpha-helices in globular proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

A topological model of the interaction between alpha-synuclein and sodium dodecyl sulfate micelles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Helix periodicity, topology, and dynamics of membrane-associated alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Involvement of electrostatic interactions in the mechanism of peptide folding induced by sodium dodecyl sulfate binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Efficient analysis of macromolecular rotational diffusion from heteronuclear relaxation data

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Alignment of Biopolymers in Strained Gels: A New Way To Create Detectable Dipole−Dipole Couplings in High-Resolution Biomolecular NMR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

The importance of not saturating water in protein NMR. Application to sensitivity enhancement and NOE measurements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

Model-Free Approach to the Dynamic Interpretation of Residual Dipolar Couplings in Globular Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507624200

21 January 2018

Identifiers

DOI

10.1074/JBC.M507624200

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24 December 2017

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24 December 2017