Molecular basis explanation for imatinib resistance of BCR-ABL due to T315I and P-loop mutations from molecular dynamics simulations (Q46703844)

24 December 2017

title

Molecular basis explanation for imatinib resistance of BCR-ABL due to T315I and P-loop mutations from molecular dynamics simulations (English)

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24 December 2017

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3

Hagop Kantarjian

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24 December 2017

5

Francis Giles

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24 December 2017

4

Jorge Cortes

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24 December 2017

6

Maher Albitar

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24 December 2017

1

Tai-Sung Lee

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24 December 2017

author name string

Steven J Potts

series ordinal

2

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24 December 2017

language of work or name

English

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publication date

1 April 2008

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24 December 2017

published in

Cancer

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24 December 2017

volume

112

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24 December 2017

issue

8

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24 December 2017

page(s)

1744-1753

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24 December 2017

Advances in the structural biology, design and clinical development of Bcr-Abl kinase inhibitors for the treatment of chronic myeloid leukaemia

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7 January 2021

The prognosis impact of BCR-ABL P-loop mutations: worse or not worse?

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Comparison of imatinib mesylate, dasatinib (BMS-354825), and nilotinib (AMN107) in an N-ethyl-N-nitrosourea (ENU)-based mutagenesis screen: high efficacy of drug combinations

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7 January 2021

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7 January 2021

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7 January 2021

AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL

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7 January 2021

Bcr-Abl resistance screening predicts a limited spectrum of point mutations to be associated with clinical resistance to the Abl kinase inhibitor nilotinib (AMN107)

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1002/CNCR.23355

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24 December 2017

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24 December 2017