The orally-active and selective c-Fms tyrosine kinase inhibitor Ki20227 inhibits disease progression in a collagen-induced arthritis mouse model (Q46846256)

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English	The orally-active and selective c-Fms tyrosine kinase inhibitor Ki20227 inhibits disease progression in a collagen-induced arthritis mouse model	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

The orally-active and selective c-Fms tyrosine kinase inhibitor Ki20227 inhibits disease progression in a collagen-induced arthritis mouse model (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

author name string

Hiroaki Ohno

1

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

Yasunori Uemura

2

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

Hideko Murooka

3

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

Hiromi Takanashi

4

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

Takemi Tokieda

5

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

Yumiko Ohzeki

6

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

Kazuo Kubo

7

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

Isao Serizawa

8

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

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publication date

1 January 2008

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

European Journal of Immunology

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

38

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

1

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

283-291

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Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

Evolving concepts of rheumatoid arthritis

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https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunisation against heterologous type II collagen induces arthritis in mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of TNF-alpha and IL-1 blockade in collagen-induced arthritis and comparison with combined anti-TNF-alpha/anti-CD4 therapy

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https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Neutralization of Vascular Endothelial Growth Factor Prevents Collagen-Induced Arthritis and Ameliorates Established Disease in Mice

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https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

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Macrophage colony-stimulating factor (M-CSF) augments cytokine induction by lipopolysaccharide (LPS)-stimulation and by bacterial infections in mice.

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https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

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Regulation of mononuclear phagocyte proliferation by colony-stimulating factor-1.

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https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

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Macrophage colony-stimulating factor stimulates survival and chemotactic behavior in isolated osteoclasts

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https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

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inferred from DOI database lookup

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

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https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

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inferred from DOI database lookup

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Rheumatoid synovial endothelial cells produce macrophage colony-stimulating factor leading to osteoclastogenesis in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

M-CSF mediates TNF-induced inflammatory osteolysis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

A c-fms tyrosine kinase inhibitor, Ki20227, suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Imatinib mesylate inhibits osteoclastogenesis and joint destruction in rats with collagen-induced arthritis (CIA)

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

TGF-beta type I receptor kinase inhibitor down-regulates rheumatoid synoviocytes and prevents the arthritis induced by type II collagen antibody.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

A highly selective inhibitor of I kappa B kinase, BMS-345541, blocks both joint inflammation and destruction in collagen-induced arthritis in mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

A CSF-1 receptor kinase inhibitor targets effector functions and inhibits pro-inflammatory cytokine production from murine macrophage populations

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Hematological characterization of congenital osteopetrosis in op/op mouse. Possible mechanism for abnormal macrophage differentiation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhanced osteoclast development in collagen-induced arthritis in interferon-gamma receptor knock-out mice as related to increased splenic CD11b+ myelopoiesis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Systemic tumor necrosis factor alpha mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor alpha-transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Macrophage- and neutrophil-dominant arthritis in human IL-1 alpha transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparative effects in vivo of recombinant murine interleukin 3, natural murine colony-stimulating factor-1, and recombinant murine granulocyte-macrophage colony-stimulating factor on myelopoiesis in mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas death receptor signaling represses monocyte numbers and macrophage activation in vivo

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Rescue of the colony-stimulating factor 1 (CSF-1)-nullizygous mouse (Csf1(op)/Csf1(op)) phenotype with a CSF-1 transgene and identification of sites of local CSF-1 synthesis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

The colony-stimulating factor 1 receptor is expressed on dendritic cells during differentiation and regulates their expansion

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Immune Interactions with CD4+ T Cells Promote the Development of Functional Osteoclasts from Murine CD11c+ Dendritic Cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic relapsing homologous collagen-induced arthritis in DBA/1 mice as a model for testing disease-modifying and remission-inducing therapies

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200737199

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/EJI.200737199

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 December 2017

http://europepmc.org/abstract/MED/18085662

ResearchGate publication ID

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