Adalimumab prevents barrier dysfunction and antagonizes distinct effects of TNF-α on tight junction proteins and signaling pathways in intestinal epithelial cells (Q46877467)

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scientific article published on 28 March 2013

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English	Adalimumab prevents barrier dysfunction and antagonizes distinct effects of TNF-α on tight junction proteins and signaling pathways in intestinal epithelial cells	scientific article published on 28 March 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/23538493

Adalimumab prevents barrier dysfunction and antagonizes distinct effects of TNF-α on tight junction proteins and signaling pathways in intestinal epithelial cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/23538493

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Andreas Fischer

1

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/23538493

author name string

Markus Gluth

2

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/23538493

Ulrich-Frank Pape

3

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/23538493

Bertram Wiedenmann

4

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/23538493

Franz Theuring

5

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/23538493

Daniel C Baumgart

6

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Europe PubMed Central

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26 December 2017

http://europepmc.org/abstract/MED/23538493

publication date

28 March 2013

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/23538493

American Journal of Physiology - Gastrointestinal and Liver Physiology

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/23538493

304

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/23538493

11

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/23538493

G970-9

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Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/23538493

TNFalpha-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFkappaB signaling

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Claudins of intestine and nephron - a correlation of molecular tight junction structure and barrier function

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Claudins and paracellular transport: an update

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Antibodies against tumor necrosis factor (TNF) induce T-cell apoptosis in patients with inflammatory bowel diseases via TNF receptor 2 and intestinal CD14⁺ macrophages.

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

The selectivity of protein kinase inhibitors: a further update

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Development of antidrug antibodies against adalimumab and association with disease activity and treatment failure during long-term follow-up

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Inflammatory bowel disease: cause and immunobiology

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Inflammatory bowel disease: clinical aspects and established and evolving therapies

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https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

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Mechanism of interferon-gamma-induced increase in T84 intestinal epithelial tight junction

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Inflammatory bowel disease and the apical junctional complex

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Cytokine regulation of tight junctions

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

The role of CDX2 in intestinal homeostasis and inflammation

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https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Role of p38 MAPK in burn-induced intestinal barrier breakdown

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer

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https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Occludin: structure, function and regulation

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Synergistic effects of interferon gamma and tumour necrosis factor alpha on T84 cell function

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Dynamics of enterocyte tight junctions: effect of experimental colitis and two different anti-TNF strategies

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Cytoskeletal regulation of epithelial barrier function during inflammation

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

TNFalpha up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding.

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Expression of tight and adherens junction proteins in ulcerative colitis associated colorectal carcinoma: upregulation of claudin-1, claudin-3, claudin-4, and beta-catenin

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Development of the Crohn's disease digestive damage score, the Lémann score

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in Caco-2 cell monolayers.

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Increase in the tight junction protein claudin-1 in intestinal inflammation

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells.

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Neutral red uptake assay for the estimation of cell viability/cytotoxicity

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Optimizing anti-TNF treatment in inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Etanercept for active Crohn's disease: a randomized, double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Tricine-SDS-PAGE.

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

AMP-activated protein kinase mediates the interferon-gamma-induced decrease in intestinal epithelial barrier function

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Epithelial tight junctions in intestinal inflammation

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Tight Junction Pore and Leak Pathways: A Dynamic Duo

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Intestinal mucosal barrier function in health and disease

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

TNFR1-induced activation of the classical NF-κB pathway

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Classical proteomics: two-dimensional electrophoresis/MALDI mass spectrometry

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Anti-TNF-α antibodies improve intestinal barrier function in Crohn's disease

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00183.2012

21 January 2018

Identifiers

10.1152/AJPGI.00183.2012

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/23538493

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 December 2017

http://europepmc.org/abstract/MED/23538493

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