Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction. (Q46941129)

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6 March 2020

title

Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction (English)

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6 March 2020

author

Carlo Gabriele Tocchetti

1

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6 March 2020

Claudio Arra

12

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6 March 2020

Fabio Di Lisa

14

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6 March 2020

Carmela Coppola

3

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Domenica Rea

5

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6 March 2020

Maria Gaia Monti

10

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Claudia De Lorenzo

11

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6 March 2020

Gerolama Condorelli

13

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6 March 2020

author name string

Andrea Carpi

2

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6 March 2020

Cristina Quintavalle

4

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Marika Campesan

6

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Antonella Arcari

7

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Giovanna Piscopo

8

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Clemente Cipresso

9

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Nicola Maurea

15

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publication date

1 April 2014

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European Journal of Heart Failure

6 March 2020

published in

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volume

16

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issue

4

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6 March 2020

page(s)

358-366

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Cancer therapy-induced cardiac toxicity in early breast cancer: addressing the unresolved issues.

6 March 2020

cites work

1 reference

Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology

21 January 2018

1 reference

Detection, monitoring, and management of trastuzumab-induced left ventricular dysfunction: an actual challenge.

21 January 2018

1 reference

Doxorubicin-induced cardiomyopathy: from molecular mechanisms to therapeutic strategies

21 January 2018

1 reference

[Na+]i handling in the failing human heart

21 January 2018

1 reference

Role of ranolazine in angina, heart failure, arrhythmias, and diabetes

21 January 2018

1 reference

Elevated cytosolic Na+ increases mitochondrial formation of reactive oxygen species in failing cardiac myocytes

21 January 2018

1 reference

Ranolazine as a cardioplegia additive improves recovery of diastolic function in isolated rat hearts

21 January 2018

1 reference

The late Na+ current (INa) inhibitor ranolazine attenuates effects of palmitoyl-L-carnitine to increase late INa and cause ventricular diastolic dysfunction.

21 January 2018

1 reference

Ranolazine, a partial fatty acid oxidation (pFOX) inhibitor, improves left ventricular function in dogs with chronic heart failure

21 January 2018

1 reference

Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure

21 January 2018

1 reference

B-type natriuretic peptide and the effect of ranolazine in patients with non-ST-segment elevation acute coronary syndromes: observations from the MERLIN-TIMI 36 (Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST Elevation Acute Corona

21 January 2018

1 reference

Comparison of preclinical cardiotoxic effects of different ErbB2 inhibitors.

21 January 2018

1 reference

Dose translation from animal to human studies revisited

21 January 2018

1 reference

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte

21 January 2018

1 reference

Na+/K+-ATPase inhibition by ouabain induces CaMKII-dependent apoptosis in adult rat cardiac myocytes

21 January 2018

1 reference

Evidence of myofibrillar protein oxidation induced by postischemic reperfusion in isolated rat hearts

21 January 2018

1 reference

Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase.

21 January 2018

1 reference

Oxidative and nitrosative stress in the maintenance of myocardial function.

21 January 2018

1 reference

Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity

21 January 2018

1 reference

Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium

21 January 2018

1 reference

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

21 January 2018

1 reference

Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro

21 January 2018

1 reference

Cancer drugs and the heart: importance and management

21 January 2018

1 reference

Elevated cytosolic Na+ decreases mitochondrial Ca2+ uptake during excitation-contraction coupling and impairs energetic adaptation in cardiac myocytes

21 January 2018

1 reference

A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation

21 January 2018

1 reference

Blocking late sodium current reduces hydrogen peroxide-induced arrhythmogenic activity and contractile dysfunction.

21 January 2018

1 reference

Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels

21 January 2018

1 reference

Hydroxyl radical-induced acute diastolic dysfunction is due to calcium overload via reverse-mode Na(+)-Ca(2+) exchange

21 January 2018

1 reference

Regulation of intracellular and mitochondrial sodium in health and disease

21 January 2018

1 reference

Ranolazine, a partial fatty acid oxidation inhibitor, reduces myocardial infarct size and cardiac troponin T release in the rat.

21 January 2018

1 reference

Nox2 NADPH oxidase promotes pathologic cardiac remodeling associated with Doxorubicin chemotherapy

21 January 2018

1 reference

Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix

21 January 2018

1 reference

Pharmacology at work for cardio-oncology: ranolazine to treat early cardiotoxicity induced by antitumor drugs

21 January 2018

1 reference

Acute doxorubicin cardiotoxicity is successfully treated with the phytochemical oleuropein through suppression of oxidative and nitrosative stress

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/EJHF.50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24464789%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference