Separase is required for chromosome segregation during meiosis I in Caenorhabditis elegans (Q47068969)

4 January 2018

title

Separase is required for chromosome segregation during meiosis I in Caenorhabditis elegans (English)

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4 January 2018

Separin homolog sep-1 CELE_Y47G6A.12

main subject

Caenorhabditis elegans

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GOA release 2020-03-11

author

Kim Nasmyth

7

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4 January 2018

author name string

Siomos MF

1

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4 January 2018

Badrinath A

2

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4 January 2018

Pasierbek P

3

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4 January 2018

Livingstone D

4

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4 January 2018

White J

5

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4 January 2018

Glotzer M

6

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4 January 2018

language of work or name

English

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publication date

1 November 2001

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4 January 2018

published in

Current Biology

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4 January 2018

volume

11

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4 January 2018

issue

23

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4 January 2018

page(s)

1825-1835

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4 January 2018

To err (meiotically) is human: the genesis of human aneuploidy

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Cohesion between sister chromatids must be established during DNA replication

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Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast

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Securin is required for chromosomal stability in human cells

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Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p

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An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast

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Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase

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A central role for cohesins in sister chromatid cohesion, formation of axial elements, and recombination during yeast meiosis.

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A Caenorhabditis elegans cohesion protein with functions in meiotic chromosome pairing and disjunction

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Disjunction of Homologous Chromosomes in Meiosis I Depends on Proteolytic Cleavage of the Meiotic Cohesin Rec8 by Separin

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Cohesin Rec8 is required for reductional chromosome segregation at meiosis

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The reduction of chromosome number in meiosis is determined by properties built into the chromosomes

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Metaphase to anaphase (mat) transition-defective mutants in Caenorhabditis elegans

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EMB-30: an APC4 homologue required for metaphase-to-anaphase transitions during meiosis and mitosis in Caenorhabditis elegans

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Activation of the anaphase-promoting complex and degradation of cyclin B is not required for progression from Meiosis I to II in Xenopus oocytes

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7 January 2021

Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family

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7 January 2021

Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsis

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7 January 2021

Incenp and an Aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis

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A sperm-supplied product essential for initiation of normal embryogenesis in Caenorhabditis elegans is encoded by the paternal-effect embryonic-lethal gene, spe-11

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Orchestrating anaphase and mitotic exit: separase cleavage and localization of Slk19

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7 January 2021

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Identifiers

DOI

1 reference

4 January 2018

1 reference

4 January 2018