Modeling the full length HIV-1 Gag polyprotein reveals the role of its p6 subunit in viral maturation and the effect of non-cleavage site mutations in protease drug resistance (Q47252759)

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scientific article published on 13 December 2017

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English	Modeling the full length HIV-1 Gag polyprotein reveals the role of its p6 subunit in viral maturation and the effect of non-cleavage site mutations in protease drug resistance	scientific article published on 13 December 2017

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

12 January 2018

http://europepmc.org/abstract/MED/29237328

Modeling the full length HIV-1 Gag polyprotein reveals the role of its p6 subunit in viral maturation and the effect of non-cleavage site mutations in protease drug resistance (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 January 2018

http://europepmc.org/abstract/MED/29237328

drug resistance

1 reference

based on heuristic

inferred from title

Chandra S Verma

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29237328%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Samuel Ken-En Gan

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29237328%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Chinh Tran-To Su

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29237328%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Chee-Keong Kwoh

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29237328%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

publication date

13 December 2017

1 reference

Europe PubMed Central

PubMed publication ID

12 January 2018

http://europepmc.org/abstract/MED/29237328

Journal of Biomolecular Structure and Dynamics

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29237328%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

36

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29237328%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

16

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29237328%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

4366-4377

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29237328%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

HIV-1 matrix organizes as a hexamer of trimers on membranes containing phosphatidylinositol-(4,5)-bisphosphate

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Basic local alignment search tool

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

NMR structure of the HIV-1 nucleocapsid protein bound to stem-loop SL2 of the psi-RNA packaging signal. Implications for genome recognition

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Natural variation in HIV-1 protease, Gag p7 and p6, and protease cleavage sites within gag/pol polyproteins: amino acid substitutions in the absence of protease inhibitors in mothers and children infected by human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

HIV Gag polyprotein: processing and early viral particle assembly

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Chemokine receptor 5 knockout strategies

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Role of Gag in HIV Resistance to Protease Inhibitors

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Prevention of HIV-1 infection with early antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Gag mutations strongly contribute to HIV-1 resistance to protease inhibitors in highly drug-experienced patients besides compensating for fitness loss

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Conformation of the HIV-1 Gag protein in solution.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

HIV-1 Gag extension: conformational changes require simultaneous interaction with membrane and nucleic acid

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Interactions between HIV-1 Gag molecules in solution: an inositol phosphate-mediated switch

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Conformation and dynamics of the Gag polyprotein of the human immunodeficiency virus 1 studied by NMR spectroscopy.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Inhibition of HIV-1 by fusion inhibitors

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Solution structure of the human immunodeficiency virus type 1 p6 protein

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

HIV-1 gag proteins: diverse functions in the virus life cycle

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

New patterns of HIV-1 resistance during HAART

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

HIV-1 protease inhibitor mutations affect the development of HIV-1 resistance to the maturation inhibitor bevirimat.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Human Immunodeficiency Virus Gag and protease: partners in resistance

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

The structural biology of HIV assembly

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Amino acid substitutions in Gag protein at non-cleavage sites are indispensable for the development of a high multitude of HIV-1 resistance against protease inhibitors

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

SPACER: Server for predicting allosteric communication and effects of regulation.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Bio3d: an R package for the comparative analysis of protein structures.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Structure-Based Statistical Mechanical Model Accounts for the Causality and Energetics of Allosteric Communication

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

AlloSigMA: allosteric signaling and mutation analysis server

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Domain-swapped dimerization of the HIV-1 capsid C-terminal domain

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Improved prediction of protein side-chain conformations with SCWRL4

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Uncoupling human immunodeficiency virus type 1 Gag and Pol reading frames: role of the transframe protein p6* in viral replication

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

HIV drug resistance on HAART despite an undetectable viral load

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Changes in human immunodeficiency virus type 1 Gag at positions L449 and P453 are linked to I50V protease mutants in vivo and cause reduction of sensitivity to amprenavir and improved viral fitness in vitro

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Association of Gag cleavage sites to protease mutations and to virological response in HIV-1 treated patients.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Expression and purification of soluble recombinant full length HIV-1 Pr55(Gag) protein in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Twenty-six years of anti-HIV drug discovery: where do we stand and where do we go?

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Development of protease inhibitors and the fight with drug-resistant HIV-1 variants

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

A conformational transition observed in single HIV-1 Gag molecules during in vitro assembly of virus-like particles.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Gag non-cleavage site mutations contribute to full recovery of viral fitness in protease inhibitor-resistant human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Elements in HIV-1 Gag contributing to virus particle assembly.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Structural basis and distal effects of Gag substrate coevolution in drug resistance to HIV-1 protease

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Gag determinants of fitness and drug susceptibility in protease inhibitor-resistant human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Contribution of the Gag-Pol transframe domain p6* and its coding sequence to morphogenesis and replication of human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Processing sites in the human immunodeficiency virus type 1 (HIV-1) Gag-Pro-Pol precursor are cleaved by the viral protease at different rates

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Force fields for protein simulations

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Substrate shape determines specificity of recognition for HIV-1 protease: analysis of crystal structures of six substrate complexes

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

I-TASSER: a unified platform for automated protein structure and function prediction

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Analytical electrostatics for biomolecules: beyond the generalized Born approximation

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Incorporating variable dielectric environments into the generalized Born model

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

HIV-1 p6 - a structured to flexible multifunctional membrane-interacting protein.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

HIV-1 assembly, budding, and maturation

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Amino acid insertions near Gag cleavage sites restore the otherwise compromised replication of human immunodeficiency virus type 1 variants resistant to protease inhibitors

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

HIV-1 antiretroviral resistance: scientific principles and clinical applications

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Protein intrinsic disorder as a flexible armor and a weapon of HIV-1.

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

I-TASSER server for protein 3D structure prediction

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2017.1417160

21 January 2018

Identifiers

10.1080/07391102.2017.1417160

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29237328%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29237328%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

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