The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection (Q47388000)

15 January 2018

title

The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection (English)

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15 January 2018

author

Alejandro Villarino

1

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15 January 2018

author name string

Linda Hibbert

2

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15 January 2018

Linda Lieberman

3

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15 January 2018

Emma Wilson

4

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15 January 2018

Tak Mak

5

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15 January 2018

Hiroki Yoshida

6

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15 January 2018

Robert A Kastelein

7

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15 January 2018

Christiaan Saris

8

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15 January 2018

Christopher A Hunter

9

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15 January 2018

language of work or name

English

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publication date

1 November 2003

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15 January 2018

published in

Immunity

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15 January 2018

volume

19

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issue

5

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15 January 2018

page(s)

645-655

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15 January 2018

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

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Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis

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Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells

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Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

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Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients

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Inhibition of Th1 Differentiation by IL-6 Is Mediated by SOCS1

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Induction of cytotoxic T lymphocyte antigen 4 (CTLA-4) restricts clonal expansion of helper T cells

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WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production

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IL-27 and IFN-αSignal via Stat1 and Stat3 and Induce T-Bet and IL-12Rβ2 in Naive T Cells

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Transcription: tantalizing times for T cells

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STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-gamma

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Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii

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T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

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Role of T-bet in commitment of TH1 cells before IL-12-dependent selection

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The lineage decisions of helper T cells

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SOCS-1 participates in negative regulation of LPS responses

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Role of interleukin-10 in regulation of T-cell-dependent and T-cell-independent mechanisms of resistance to Toxoplasma gondii

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Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox

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7 January 2021

Disruption of T helper 2-immune responses in Epstein-Barr virus-induced gene 3-deficient mice

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7 January 2021

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7 January 2021

IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

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7 January 2021

Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

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7 January 2021

Interleukin-12: a cytokine at the interface of inflammation and immunity

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7 January 2021

Interleukin-12 and the regulation of innate resistance and adaptive immunity

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7 January 2021

STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity

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7 January 2021

Specific ablation of Stat3beta distorts the pattern of Stat3-responsive gene expression and impairs recovery from endotoxic shock

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7 January 2021

WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection

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7 January 2021

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Identifiers

DOI

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15 January 2018

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15 January 2018