Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein (Q47791886)

5 February 2018

title

Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein (English)

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5 February 2018

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Liang SH

1

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5 February 2018

Hong D

series ordinal

2

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5 February 2018

Clarke MF

series ordinal

3

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5 February 2018

language of work or name

English

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publication date

1 July 1998

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5 February 2018

Journal of Biological Chemistry

published in

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5 February 2018

volume

273

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5 February 2018

issue

31

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5 February 2018

page(s)

19817-19821

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5 February 2018

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

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T antigen is bound to a host protein in SY40-transformed cells

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p53, the cellular gatekeeper for growth and division

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p53: puzzle and paradigm

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Sequence-specific transcriptional activation is essential for growth suppression by p53.

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WAF1, a potential mediator of p53 tumor suppression

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The p53-mdm-2 autoregulatory feedback loop

21 January 2018

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

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Induction of the growth inhibitor IGF-binding protein 3 by p53

21 January 2018

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p53 mutations in human cancers

21 January 2018

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The p53 tumour suppressor gene

21 January 2018

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Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport

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Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion

21 January 2018

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Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

21 January 2018

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Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis

21 January 2018

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Cytoplasmically sequestered wild-type p53 protein in neuroblastoma is relocated to the nucleus by a C-terminal peptide

21 January 2018

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c-myc and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle

21 January 2018

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Green fluorescent protein as a marker for gene expression

21 January 2018

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Suppression of human colorectal carcinoma cell growth by wild-type p53

21 January 2018

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Evidence using a green fluorescent protein-glucocorticoid receptor chimera that the Ran/TC4 GTPase mediates an essential function independent of nuclear protein import

21 January 2018

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Wild-type p53 is a cell cycle checkpoint determinant following irradiation

21 January 2018

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Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2

21 January 2018

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Structural aspects of the p53 protein in relation to gene evolution: a second look.

21 January 2018

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Regulation of the specific DNA binding function of p53

21 January 2018

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Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases

21 January 2018

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Nucleocytoplasmic transport

21 January 2018

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A GTPase controlling nuclear trafficking: running the right way or walking RANdomly?

21 January 2018

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High-resolution structure of the oligomerization domain of p53 by multidimensional NMR

21 January 2018

1 reference

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Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

21 January 2018

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The Bcl-2 family of proteins: regulators of cell death and survival

21 January 2018

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The effect of protein context on nuclear location signal function

21 January 2018

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The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.31.19817

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5 February 2018

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5 February 2018