Human neutrophil elastase mediates fibrinolysis shutdown through competitive degradation of plasminogen and generation of angiostatin (Q47911192)

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scientific article published on 23 August 2017

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English	Human neutrophil elastase mediates fibrinolysis shutdown through competitive degradation of plasminogen and generation of angiostatin	scientific article published on 23 August 2017

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PubMed publication ID

28837538

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6 February 2018

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http://europepmc.org/abstract/MED/28837538

title

Human neutrophil elastase mediates fibrinolysis shutdown through competitive degradation of plasminogen and generation of angiostatin (English)

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28837538

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6 February 2018

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Christopher D Barrett

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1

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28837538

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Hunter B Moore

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2

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28837538

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6 February 2018

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Anirban Banerjee

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3

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28837538

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Christopher C Silliman

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4

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28837538

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Ernest E Moore

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5

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28837538

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http://europepmc.org/abstract/MED/28837538

Michael B Yaffe

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6

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28837538

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publication date

23 August 2017

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28837538

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http://europepmc.org/abstract/MED/28837538

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The Journal of Trauma and Acute Care Surgery

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PubMed publication ID

28837538

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6 February 2018

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http://europepmc.org/abstract/MED/28837538

volume

83

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Europe PubMed Central

PubMed publication ID

28837538

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6 February 2018

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http://europepmc.org/abstract/MED/28837538

issue

6

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Europe PubMed Central

PubMed publication ID

28837538

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6 February 2018

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http://europepmc.org/abstract/MED/28837538

page(s)

1053-1061

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28837538

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6 February 2018

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http://europepmc.org/abstract/MED/28837538

cites work

Overwhelming tPA release, not PAI-1 degradation, is responsible for hyperfibrinolysis in severely injured trauma patients

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PubMed Central

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26 August 2018

Viscoelastic measurements of platelet function, not fibrinogen function, predicts sensitivity to tissue-type plasminogen activator in trauma patients

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26 August 2018

Fibrinolysis shutdown phenotype masks changes in rodent coagulation in tissue injury versus hemorrhagic shock

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26 August 2018

Plasma is the physiologic buffer of tissue plasminogen activator-mediated fibrinolysis: rationale for plasma-first resuscitation after life-threatening hemorrhage

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26 August 2018

Comprehensive evaluation of coagulation in swine subjected to isolated primary blast injury

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26 August 2018

Hemolysis exacerbates hyperfibrinolysis, whereas platelolysis shuts down fibrinolysis: evolving concepts of the spectrum of fibrinolysis in response to severe injury

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26 August 2018

Hyperfibrinolysis, physiologic fibrinolysis, and fibrinolysis shutdown: the spectrum of postinjury fibrinolysis and relevance to antifibrinolytic therapy

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26 August 2018

Coagulofibrinolytic changes in patients with disseminated intravascular coagulation associated with post-cardiac arrest syndrome--fibrinolytic shutdown and insufficient activation of fibrinolysis lead to organ dysfunction

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26 August 2018

The X-ray crystal structure of full-length human plasminogen

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26 August 2018

Model thrombi formed under flow reveal the role of factor XIII-mediated cross-linking in resistance to fibrinolysis

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26 August 2018

Molecular mechanisms of fibrinolysis.

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26 August 2018

Role of angiogenesis in tumor growth and metastasis

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26 August 2018

Angiostatin inhibits endothelial and melanoma cellular invasion by blocking matrix-enhanced plasminogen activation

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26 August 2018

Kringle domains of human angiostatin. Characterization of the anti-proliferative activity on endothelial cells

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26 August 2018

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

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26 August 2018

Elastase-mediated fibrinogenolysis by chemoattractant-stimulated neutrophils occurs in the presence of physiologic concentrations of antiproteinases

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26 August 2018

Lys-plasminogen is a significant intermediate in the activation of Glu-plasminogen during fibrinolysis in vitro

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Sensitive substrates for human leukocyte and porcine pancreatic elastase: A study of the merits of various chromophoric and fluorogenic leaving groups in assays for serine proteases

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26 August 2018

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

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26 August 2018

The human plasma fibrinolytic system: Regulation and control

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26 August 2018

Generation of Biologically Active Angiostatin Kringle 1-3 by Activated Human Neutrophils

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28837538

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The binding of human plasminogen to fibrin and fibrinogen

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28837538

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postinjury neutrophil priming and activation: An early vulnerable window*

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28837538

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complexing of tissue plasminogen activator with PAI-1, alpha 2-macroglobulin, and C1-inhibitor: studies in patients with defibrination and a fibrinolytic state after electroshock or complicated labor

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28837538

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disseminated intravascular coagulation at an early phase of trauma is associated with consumption coagulopathy and excessive fibrinolysis both by plasmin and neutrophil elastase

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28837538

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphonuclear neutrophil chemiluminescence in whole blood from blunt trauma patients with multiple injuries

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28837538

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of factor XIII by human neutrophil elastase results in a novel active truncated form of factor XIII A subunit

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28837538

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated tissue plasminogen activator and reduced plasminogen activator inhibitor promote hyperfibrinolysis in trauma patients

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28837538

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Priming of the neutrophil respiratory burst is species-dependent and involves MAP kinase activation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28837538

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil priming for elastase release in adult blunt trauma patients

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/28837538

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1097/TA.0000000000001685

1 reference

stated in

Europe PubMed Central

PubMed publication ID

28837538

retrieved

6 February 2018

reference URL

http://europepmc.org/abstract/MED/28837538

PMC publication ID

5767103

0 references

PubMed publication ID

28837538

1 reference

stated in

Europe PubMed Central

PubMed publication ID

28837538

retrieved

6 February 2018

reference URL

http://europepmc.org/abstract/MED/28837538

 

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