Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation (Q47936908)

6 February 2018

title

Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation (English)

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6 February 2018

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6

Glenn C Telling

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6 February 2018

Tanya Seward

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object named as

Tanya Seward

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6 February 2018

author name string

Rajgopal Yadavalli

1

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6 February 2018

Rodney P Guttmann

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Adrian P Centers

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R Anthony Williamson

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language of work or name

English

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publication date

16 March 2004

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6 February 2018

Journal of Biological Chemistry

published in

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volume

279

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issue

21

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page(s)

21948-21956

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6 February 2018

Truncated forms of the human prion protein in normal brain and in prion diseases

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

21 January 2018

Transmission of prions

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

A cellular gene encodes scrapie PrP 27-30 protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Purification and properties of the cellular prion protein from Syrian hamster brain

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Processing of a cellular prion protein: identification of N- and C-terminal cleavage sites.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

The calpain family and human disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400793200

Distinct cleavage patterns of normal and pathologic forms of alpha-synuclein by calpain I in vitro

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Pharmacological approaches to prion research

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Evidence for the multiplication of scrapie agent in cell culture

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Scrapie strains maintain biological phenotypes on propagation in a cell line in culture

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Cultured cell sublines highly susceptible to prion infection

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Cell-penetrating inhibitors of calpain

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Measurement of the scrapie agent using an incubation time interval assay

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400793200

A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400793200

Site-directed mutagenesis of alpha II spectrin at codon 1175 modulates its mu-calpain susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400793200

The sensitivity of c-Jun and c-Fos proteins to calpains depends on conformational determinants of the monomers and not on formation of dimers

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Calpains: intact and active?

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Scrapie prions alter receptor-mediated calcium responses in cultured cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M400793200

Calpain II colocalizes with detergent-insoluble rafts on human and Jurkat T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M400793200

21 January 2018

Identifiers

DOI

10.1074/JBC.M400793200

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6 February 2018

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6 February 2018