Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease (Q47942475)

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scientific article published on 24 July 2013

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English	Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease	scientific article published on 24 July 2013

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scholarly article

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Europe PubMed Central

PubMed publication ID

23883936

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7 February 2018

reference URL

http://europepmc.org/abstract/MED/23883936

retracted paper

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Dataset for "Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine"

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Continued use of retracted papers: Temporal trends in citations and (lack of) awareness of retractions shown in citation contexts in biomedicine

title

Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease (English)

1 reference

stated in

Europe PubMed Central

PubMed publication ID

23883936

retrieved

7 February 2018

reference URL

http://europepmc.org/abstract/MED/23883936

main subject

genomics

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author

Joseph H. Lee

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Joseph H Lee

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5

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author name string

Herve Rhinn

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1

1 reference

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Europe PubMed Central

PubMed publication ID

23883936

retrieved

7 February 2018

reference URL

http://europepmc.org/abstract/MED/23883936

Ryousuke Fujita

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2

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Europe PubMed Central

PubMed publication ID

23883936

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7 February 2018

reference URL

http://europepmc.org/abstract/MED/23883936

Liang Qiang

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3

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Europe PubMed Central

PubMed publication ID

23883936

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7 February 2018

reference URL

http://europepmc.org/abstract/MED/23883936

Rong Cheng

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4

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Europe PubMed Central

PubMed publication ID

23883936

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7 February 2018

reference URL

http://europepmc.org/abstract/MED/23883936

Asa Abeliovich

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6

1 reference

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Europe PubMed Central

PubMed publication ID

23883936

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7 February 2018

reference URL

http://europepmc.org/abstract/MED/23883936

language of work or name

English

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publication date

24 July 2013

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stated in

Europe PubMed Central

PubMed publication ID

23883936

retrieved

7 February 2018

reference URL

http://europepmc.org/abstract/MED/23883936

published in

Nature

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stated in

Europe PubMed Central

PubMed publication ID

23883936

retrieved

7 February 2018

reference URL

http://europepmc.org/abstract/MED/23883936

volume

500

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stated in

Europe PubMed Central

PubMed publication ID

23883936

retrieved

7 February 2018

reference URL

http://europepmc.org/abstract/MED/23883936

issue

7460

1 reference

stated in

Europe PubMed Central

PubMed publication ID

23883936

retrieved

7 February 2018

reference URL

http://europepmc.org/abstract/MED/23883936

page(s)

45-50

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Europe PubMed Central

PubMed publication ID

23883936

retrieved

7 February 2018

reference URL

http://europepmc.org/abstract/MED/23883936

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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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Enhanced amyloidogenic metabolism of the amyloid beta-protein precursor in the X11L-deficient mouse brain.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23883936

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Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23883936

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Cotrafficking of SV2 and synaptotagmin at the synapse.

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In VivoAssessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life

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https://pubmed.ncbi.nlm.nih.gov/23883936

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Interactome mapping suggests new mechanistic details underlying Alzheimer's disease

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The novel membrane protein TMEM59 modulates complex glycosylation, cell surface expression, and secretion of the amyloid precursor protein

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A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging

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Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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Use of cDNA microarray in the search for molecular markers involved in the onset of Alzheimer's disease dementia

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https://pubmed.ncbi.nlm.nih.gov/23883936

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The NCBI dbGaP database of genotypes and phenotypes

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https://pubmed.ncbi.nlm.nih.gov/23883936

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Housekeeping while brain's storming Validation of normalizing factors for gene expression studies in a murine model of traumatic brain injury

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12 December 2020

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Regulatory impact factors: unraveling the transcriptional regulation of complex traits from expression data.

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12 December 2020

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Concerted perturbation observed in a hub network in Alzheimer's disease

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study

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12 December 2020

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Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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Common genetic variation and performance on standardized cognitive tests

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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Ways toward an early diagnosis in Alzheimer's disease: the Alzheimer's Disease Neuroimaging Initiative (ADNI).

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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A differential wiring analysis of expression data correctly identifies the gene containing the causal mutation.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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Memory complaints and APOE-epsilon4 accelerate cognitive decline in cognitively normal elderly

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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Genome-wide association of lipid-lowering response to statins in combined study populations

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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Patterns of brain activation in people at risk for Alzheimer's disease.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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Apolipoprotein E: far more than a lipid transport protein

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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inferred from PubMed ID database lookup

Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

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PubMed

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12 December 2020

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inferred from PubMed ID database lookup

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23883936

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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Apolipoprotein receptor 2 and X11 alpha/beta mediate apolipoprotein E-induced endocytosis of amyloid-beta precursor protein and beta-secretase, leading to amyloid-beta production

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PubMed

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Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

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PubMed

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Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease

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Toward a remembrance of things past: deciphering Alzheimer disease.

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Analysis of Alzheimer's disease severity across brain regions by topological analysis of gene co-expression networks

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PubMed

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Transcriptomic analysis of autistic brain reveals convergent molecular pathology

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Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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Integrated weighted gene co-expression network analysis with an application to chronic fatigue syndrome

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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PLINK: a tool set for whole-genome association and population-based linkage analyses

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23883936

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inferred from PubMed ID database lookup

Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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inferred from PubMed ID database lookup

BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic control of human brain transcript expression in Alzheimer disease

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons

1 reference

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PubMed

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12 December 2020

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A hundred years of Alzheimer's disease research

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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

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Alternative α-synuclein transcript usage as a convergent mechanism in Parkinson's disease pathology

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12 December 2020

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inferred from PubMed ID database lookup

Use of Florbetapir-PET for Imaging β-Amyloid Pathology

1 reference

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PubMed

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inferred from PubMed ID database lookup

ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

1 reference

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12 December 2020

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Fyn modulation of Dab1 effects on amyloid precursor protein and ApoE receptor 2 processing

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Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

retrieved

12 December 2020

based on heuristic

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Apolipoprotein E and Alzheimer disease.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23883936

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam

1 reference

stated in

PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/23883936

retrieved

12 December 2020

based on heuristic

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Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/23883936

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12 December 2020

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Identifiers

DOI

10.1038/NATURE12415

1 reference

stated in

Europe PubMed Central

PubMed publication ID

23883936

retrieved

7 February 2018

reference URL

http://europepmc.org/abstract/MED/23883936

Dimensions Publication ID

1040614698

0 references

PubMed publication ID

23883936

1 reference

stated in

Europe PubMed Central

PubMed publication ID

23883936

retrieved

7 February 2018

reference URL

http://europepmc.org/abstract/MED/23883936

ResearchGate publication ID

251877344

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