The RNA-binding protein HuR regulates the expression of cyclooxygenase-2. (Q47963945)

7 February 2018

title

The RNA-binding protein HuR regulates the expression of cyclooxygenase-2. (English)

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7 February 2018

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6

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author name string

Sibani Sengupta

1

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Byeong-Churl Jang

2

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Ming-Tao Wu

3

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Ji-Hye Paik

4

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Henry Furneaux

5

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language of work or name

English

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publication date

18 April 2003

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Journal of Biological Chemistry

published in

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volume

278

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issue

27

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page(s)

25227-25233

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Regulation of mRNA stability in mammalian cells

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Human cyclooxygenase-2 cDNA

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Cyclooxygenases 1 and 2

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Down-regulation of cytokine-induced cyclo-oxygenase-2 transcript isoforms by dexamethasone: evidence for post-transcriptional regulation

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Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3'-untranslated region

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Immediate-early MEK-1-dependent stabilization of rat smooth muscle cell cyclooxygenase-2 mRNA by Galpha(q)-coupled receptor signaling

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Serum withdrawal-induced post-transcriptional stabilization of cyclooxygenase-2 mRNA in MDA-MB-231 mammary carcinoma cells requires the activity of the p38 stress-activated protein kinase

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Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38.

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Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade

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The Elav-like proteins bind to AU-rich elements and to the poly(A) tail of mRNA

21 January 2018

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RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

21 January 2018

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A broader role for AU-rich element-mediated mRNA turnover revealed by a new transcriptional pulse strategy

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Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs

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HuR regulates p21 mRNA stabilization by UV light

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Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein

21 January 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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A U-rich element in the 5' untranslated region is necessary for the translation of p27 mRNA.

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Developmental regulation of RNA transcript destabilization by A + U-rich elements is AUF1-dependent

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The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR.

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Structural basis for recognition of AU-rich element RNA by the HuD protein

21 January 2018

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Delineation of mRNA export pathways by the use of cell-permeable peptides

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The 3'-untranslated region of murine cyclooxygenase-2 contains multiple regulatory elements that alter message stability and translational efficiency

21 January 2018

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p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes

21 January 2018

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Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR

21 January 2018

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Kinetic and thermodynamic characterization of the R17 coat protein-ribonucleic acid interaction

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M301813200

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7 February 2018

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7 February 2018