Signaling mechanisms through gp130: a model of the cytokine system (Q47992455)

7 February 2018

review article

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title

Signaling mechanisms through gp130: a model of the cytokine system (English)

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7 February 2018

author name string

Hirano T

series ordinal

1

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7 February 2018

Nakajima K

series ordinal

2

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7 February 2018

Hibi M

series ordinal

3

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7 February 2018

publication date

1 December 1997

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7 February 2018

Cytokine and Growth Factor Reviews

published in

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7 February 2018

volume

8

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7 February 2018

issue

4

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7 February 2018

page(s)

241-252

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7 February 2018

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

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Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

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Molecular cloning and expression of an IL-6 signal transducer, gp130

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Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes

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7 January 2021

Homology of the p40 subunit of natural killer cell stimulatory factor (NKSF) with the extracellular domain of the interleukin-6 receptor

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7 January 2021

Released Form of CNTF Receptor α Component as a Soluble Mediator of CNTF Responses

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7 January 2021

Functional expression of soluble human interleukin-11 (IL-11) receptor alpha and stoichiometry of in vitro IL-11 receptor complexes with gp130

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Extramedullary expansion of hematopoietic progenitor cells in interleukin (IL)-6-sIL-6R double transgenic mice

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Characterization of a multicomponent receptor for GDNF.

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GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF

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A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor

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Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase.

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A bioactive designer cytokine for human hematopoietic progenitor cell expansion

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A protein tyrosine kinase in the interferon alpha/beta signaling pathway

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7 January 2021

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

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7 January 2021

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

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7 January 2021

Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

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7 January 2021

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

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Interleukin-6-induced tyrosine phosphorylation of multiple proteins in murine hematopoietic lineage cells

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Tyrosine phosphorylation of JAK-TYK kinases in malignant plasma cell lines growth-stimulated by interleukins 6 and 11

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A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

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Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

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7 January 2021

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

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7 January 2021

Transcriptional activation of the IL-6 response element in the junB promoter is mediated by multiple Stat family proteins

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7 January 2021

Signal transduction through IL-6 receptor: involvement of multiple protein kinases, stat factors, and a novel H7-sensitive pathway

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STAT3 and STAT5B are targets of two different signal pathways activated by hematopoietin receptors and control transcription via separate cytokine response elements

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7 January 2021

An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT.

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7 January 2021

IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP

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7 January 2021

Acute-Phase Response Factor, a Nuclear Factor Binding to Acute-Phase Response Elements, is Rapidly Activated by Interleukin-6 at the Posttranslational Level

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7 January 2021

Identification of a novel interleukin-6 response element containing an Ets-binding site and a CRE-like site in the junB promoter

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7 January 2021

Requirement of serine phosphorylation for formation of STAT-promoter complexes

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7 January 2021

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

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7 January 2021

Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins

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7 January 2021

STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFNAR1 chain of the type I interferon receptor

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7 January 2021

Examination of the potential functional role of conserved cysteine residues in the hormone binding domain of the human 1,25-dihydroxyvitamin D3 receptor.

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7 January 2021

Syp associates with gp130 and Janus kinase 2 in response to interleukin-11 in 3T3-L1 mouse preadipocytes

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7 January 2021

Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.

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7 January 2021

Gp130-mediated signal transduction in embryonic stem cells involves activation of Jak and Ras/mitogen-activated protein kinase pathways

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7 January 2021

Activation of Fes tyrosine kinase by gp130, an interleukin-6 family cytokine signal transducer, and their association

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7 January 2021

Tec tyrosine kinase links the cytokine receptors to PI-3 kinase probably through JAK

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7 January 2021

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

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7 January 2021

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

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7 January 2021

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

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7 January 2021

An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth

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7 January 2021

Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases

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7 January 2021

Janus kinase-dependent activation of insulin receptor substrate 1 in response to interleukin-4, oncostatin M, and the interferons

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7 January 2021

Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases

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7 January 2021

Growth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling

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7 January 2021

Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation

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7 January 2021

Multiple regions within the cytoplasmic domains of the leukemia inhibitory factor receptor and gp130 cooperate in signal transduction in hepatic and neuronal cells

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7 January 2021

Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells

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7 January 2021

Recombinant human interleukin 6 (B-cell stimulatory factor 2) is a potent inducer of differentiation of mouse myeloid leukemia cells (M1)

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7 January 2021

Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/interleukin 6

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7 January 2021

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Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

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7 January 2021

cDNA cloning of murine interleukin-HP1: homology with human interleukin 6.

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7 January 2021

Interleukin 6 (IL-6) and its receptor: their role in plasma cell neoplasias

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7 January 2021

A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells

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7 January 2021

Involvement of STAT3 in the granulocyte colony-stimulating factor-induced differentiation of myeloid cells

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7 January 2021

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

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7 January 2021

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7 January 2021

Induction of neurite outgrowth by interleukin-6 is accompanied by activation of Stat3 signaling pathway in a variant PC12 cell (E2) line

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7 January 2021

Identification of interleukin-6 as a factor that induces neurite outgrowth by PC12 cells primed with NGF

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7 January 2021

Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin-6.

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7 January 2021

Leukemia inhibitory factor-dependent transcriptional activation in embryonic stem cells

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7 January 2021

STATs: signal transducers and activators of transcription

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7 January 2021

Jaks, STATs, Cytokine Signal Transduction, and Immunoregulation: Are We There Yet?

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7 January 2021

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

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7 January 2021

PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity

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7 January 2021

The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase.

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7 January 2021

STAT3beta, a splice variant of transcription factor STAT3, is a dominant negative regulator of transcription

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7 January 2021

Naturally occurring dominant negative variants of Stat5.

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7 January 2021

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

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7 January 2021

PTP1D is a positive regulator of the prolactin signal leading to beta-casein promoter activation.

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7 January 2021

A family of proteins that inhibit signalling through tyrosine kinase receptors

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7 January 2021

A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion

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7 January 2021

A family of cytokine-inducible inhibitors of signalling

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7 January 2021

A new protein containing an SH2 domain that inhibits JAK kinases

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7 January 2021

Structure and function of a new STAT-induced STAT inhibitor

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7 January 2021

10.1016/S1359-6101(98)80005-1

Identifiers

DOI

1 reference

7 February 2018

1 reference

7 February 2018