Neurofibrillary pathology of Alzheimer's disease and other tauopathies. (Q48291136)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9932415%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

review article

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title

Neurofibrillary pathology of Alzheimer's disease and other tauopathies (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9932415%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

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M Goedert

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9932415%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

publication date

1 January 1998

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9932415%20AND%20SRC:MED&resulttype=core&format=json

Progress in Brain Research

9 December 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9932415%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

volume

117

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9 December 2019

page(s)

287-306

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Paired helical filament-like phosphorylation of tau, deposition of beta/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A

9 December 2019

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Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

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7 January 2021

Paired helical filament tau (PHFtau) in Niemann-Pick type C disease is similar to PHFtau in Alzheimer's disease

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7 January 2021

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

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7 January 2021

Chromosome 17 and hereditary dementia: linkage studies in three non-Alzheimer families and kindreds with late-onset FAD.

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Neuropathological stageing of Alzheimer-related changes

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7 January 2021

A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads

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Frequency of stages of Alzheimer-related lesions in different age categories

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7 January 2021

Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding

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7 January 2021

Developmental changes in tau phosphorylation: fetal tau is transiently phosphorylated in a manner similar to paired helical filament-tau characteristic of Alzheimer's disease.

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7 January 2021

Pathological tau proteins in postencephalitic parkinsonism: comparison with Alzheimer's disease and other neurodegenerative disorders

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Tau protein binds to microtubules through a flexible array of distributed weak sites

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7 January 2021

Genetic evidence for the involvement of tau in progressive supranuclear palsy

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7 January 2021

Glial inclusions in CNS degenerative diseases.

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7 January 2021

Primary structure of high molecular weight tau present in the peripheral nervous system

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7 January 2021

Straight and paired helical filaments in Alzheimer disease have a common structural unit

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7 January 2021

The microtubule binding repeats of tau protein assemble into filaments like those found in Alzheimer's disease

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7 January 2021

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

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7 January 2021

Are neuronal intranuclear inclusions the common neuropathology of triplet-repeat disorders with polyglutamine-repeat expansions?

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7 January 2021

Specific pathological Tau protein variants characterize Pick's disease.

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7 January 2021

Identification of normal and pathological aging in prospectively studied nondemented elderly humans

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7 January 2021

MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption

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7 January 2021

Characterization of two pathological tau protein, variants in Alzheimer brain cortices.

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7 January 2021

Abnormal Tau proteins in progressive supranuclear palsy. Similarities and differences with the neurofibrillary degeneration of the Alzheimer type.

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7 January 2021

Modulation of the phosphorylation state of tau in situ: the roles of calcium and cyclic AMP.

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7 January 2021

Sequestration of RNA in Alzheimer's disease neurofibrillary tangles and senile plaques.

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7 January 2021

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

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7 January 2021

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

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7 January 2021

Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

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7 January 2021

Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system

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7 January 2021

p42 map kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1Implications for Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development

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https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

Protein Phosphatase 2A Is the Major Enzyme in Brain that Dephosphorylates τ Protein Phosphorylated by Proline‐Directed Protein Kinases or Cyclic AMP‐Dependent Protein Kinase

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7 January 2021

Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans

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7 January 2021

Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases

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7 January 2021

Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau.

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7 January 2021

A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis

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7 January 2021

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase

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7 January 2021

Altered microtubule organization in small-calibre axons of mice lacking tau protein

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7 January 2021

Characterization of Two Distinct Monoclonal Antibodies to Paired Helical Filaments: Further Evidence for Fetal‐Type Phosphorylation of the τ in Paired Helical Filaments

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7 January 2021

Characterization of mAb AP422, a novel phosphorylation-dependent monoclonal antibody against tau protein

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7 January 2021

Alzheimer-like changes in microtubule-associated protein Tau induced by sulfated glycosaminoglycans. Inhibition of microtubule binding, stimulation of phosphorylation, and filament assembly depend on the degree of sulfation

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7 January 2021

Tau proteins: the molecular structure and mode of binding on microtubules

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7 January 2021

Unique Alzheimer's disease paired helical filament specific epitopes involve double phosphorylation at specific sites.

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7 January 2021

Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3.

1 reference

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7 January 2021

Unusual case of corticobasal degeneration with tau/Gallyas-positive neuronal and glial tangles

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7 January 2021

MHP1, an essential gene in Saccharomyces cerevisiae required for microtubule function

1 reference

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7 January 2021

RNA stimulates aggregation of microtubule-associated protein tau into Alzheimer-like paired helical filaments

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

Fetal-type phosphorylation of the tau in paired helical filaments

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

The extent of phosphorylation of fetal tau is comparable to that of PHF-tau from Alzheimer paired helical filaments

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

The carboxyl third of tau is tightly bound to paired helical filaments.

1 reference

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7 January 2021

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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7 January 2021

Implication of brain cdc2 and MAP2 kinases in the phosphorylation of tau protein in Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

The primary structure and heterogeneity of tau protein from mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

Microtubule-associated protein MAP2 shares a microtubule binding motif with tau protein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-356.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

Neurofibrillary tangles in Niemann-Pick disease type C

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

Phosphorylation of tau by glycogen synthase kinase-3β in intact mammalian cells: The effects on the organization and stability of microtubules

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

1 reference

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7 January 2021

Site-specific dephosphorylation of tau protein at Ser202/Thr205 in response to microtubule depolymerization in cultured human neurons involves protein phosphatase 2A.

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7 January 2021

Proline-directed and non-proline-directed phosphorylation of PHF-tau.

1 reference

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7 January 2021

PHF-tau from Alzheimer's brain comprises four species on SDS-PAGE which can be mimicked by in vitro phosphorylation of human brain tau by glycogen synthase kinase-3 beta.

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7 January 2021

Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons

1 reference

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7 January 2021

Familial multiple-system tauopathy with presenile dementia is localized to chromosome 17

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7 January 2021

Glial fibrillary tangles with straight tubules in the brains of patients with progressive supranuclear palsy

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7 January 2021

Polymerization of tau into filaments in the presence of heparin: the minimal sequence required for tau-tau interaction

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7 January 2021

Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease

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7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

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7 January 2021

Pick's disease: hyperphosphorylated tau protein segregates to the somatoaxonal compartment

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7 January 2021

Effect of heparin on phosphorylation site specificity of neuronal Cdc2-like kinase

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7 January 2021

Two-dimensional characterization of paired helical filament-tau from Alzheimer's disease: demonstration of an additional 74-kDa component and age-related biochemical modifications.

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7 January 2021

Different distribution of phosphorylated tau protein isoforms in Alzheimer's and Pick's diseases.

1 reference

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7 January 2021

Detection of Phosphorylated Ser262 in Fetal Tau, Adult Tau, and Paired Helical Filament Tau

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7 January 2021

The neuropathology of chromosome 17-linked dementia

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7 January 2021

Cationic dyes reveal proteoglycans structurally integrated within the characteristic lesions of Alzheimer's disease

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7 January 2021

A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle

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7 January 2021

Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A.

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7 January 2021

Comparison of the neurofibrillary pathology in Alzheimer's disease and familial presenile dementia with tangles

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7 January 2021

Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments

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7 January 2021

Alpha-synuclein in Lewy bodies

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7 January 2021

Neurofibrillary tangles in Niemann-Pick disease type C.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

A68 is a component of paired helical filaments of Gerstmann-Sträussler-Scheinker disease, Indiana kindred

1 reference

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7 January 2021

Argyrophilic grain disease: widespread hyperphosphorylation of tau protein in limbic neurons

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7 January 2021

Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro

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7 January 2021

Structural characterization of the core of the paired helical filament of Alzheimer disease

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7 January 2021

Detection of tau proteins in normal and Alzheimer's disease cerebrospinal fluid with a sensitive sandwich enzyme-linked immunosorbent assay.

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7 January 2021

Specific tau variants in the brains of patients with myotonic dystrophy

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7 January 2021

Localization of the gene for rapidly progressive autosomal dominant parkinsonism and dementia with pallido-ponto-nigral degeneration to chromosome 17q21

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7 January 2021

Appearance of paired nucleated, Tau-positive glia in patients with progressive supranuclear palsy brain tissue

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7 January 2021

Tau in paired helical filaments is functionally distinct from fetal tau: assembly incompetence of paired helical filament-tau

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

Neurofibrillary tangles in progressive supranuclear palsy contain the same tau epitopes identified in Alzheimer's disease PHFtau.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2964022-4

7 January 2021

10.1016/S0079-6123(08)64022-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9932415%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

1 reference