Apolipoprotein E and low density lipoprotein receptor-related protein facilitate intraneuronal Abeta42 accumulation in amyloid model mice (Q48408205)

11 February 2018

title

Apolipoprotein E and low density lipoprotein receptor-related protein facilitate intraneuronal Abeta42 accumulation in amyloid model mice (English)

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7

David M Holtzman

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Celina V Zerbinatti

1

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Suzanne E Wahrle

2

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Hyungjin Kim

3

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Judy A Cam

4

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Kelly Bales

5

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Steven M Paul

6

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Guojun Bu

8

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language of work or name

English

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publication date

29 September 2006

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Journal of Biological Chemistry

published in

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volume

281

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issue

47

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page(s)

36180-36186

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11 February 2018

Distribution of the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein in human tissues

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

LRP: a multifunctional scavenger and signaling receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Cell surface APP751 forms complexes with protease nexin 2 ligands and is internalized via the low density lipoprotein receptor-related protein (LRP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

The cytoplasmic domain of the LDL receptor-related protein regulates multiple steps in APP processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Self-assembly of HEK cell-secreted ApoE particles resembles ApoE enrichment of lipoproteins as a ligand for the LDL receptor-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Nerve growth factor induces rapid increases in functional cell surface low density lipoprotein receptor-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Cellular catabolism of lipid poor apolipoprotein E via cell surface LDL receptor-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Abeta42-positive non-pyramidal neurons around amyloid plaques in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Intraneuronal Abeta42 accumulation in human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Early intraneuronal Abeta deposition in the hippocampus of APP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Intracellular amyloid-beta 1-42, but not extracellular soluble amyloid-beta peptides, induces neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Selective cytotoxicity of intracellular amyloid beta peptide1-42 through p53 and Bax in cultured primary human neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Intracellular mechanisms of amyloid accumulation and pathogenesis in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Abeta localization in abnormal endosomes: association with earliest Abeta elevations in AD and Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Subcellular topography of neuronal Abeta peptide in APPxPS1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Role of LRP in TGFbeta2-mediated neuronal uptake of Abeta and effects on memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604436200

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M604436200

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M604436200

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M604436200

21 January 2018

Identifiers

DOI

10.1074/JBC.M604436200

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11 February 2018

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11 February 2018