Rescue of dying neurons: A new action for deprenyl in MPTP parkinsonism (Q48620615)

13 February 2018

title

Rescue of dying neurons: A new action for deprenyl in MPTP parkinsonism (English)

1 reference

https://api.crossref.org/works/10.1002/JNR.490300410

29 October 2022

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686284

29 October 2022

author name string

W. G. Tatton

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686284

29 October 2022

C. E. Greenwood

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686284

29 October 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1686284

29 October 2022

publication date

1 December 1991

1 reference

13 February 2018

full work available at URL

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjnr.490300410

1 reference

https://api.crossref.org/works/10.1002/JNR.490300410

https://onlinelibrary.wiley.com/doi/full/10.1002/jnr.490300410

29 October 2022

1 reference

https://api.crossref.org/works/10.1002/JNR.490300410

Journal of Neuroscience Research

29 October 2022

published in

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13 February 2018

volume

30

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13 February 2018

issue

4

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13 February 2018

page(s)

666-672

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13 February 2018

The potentiation of the anti akinetic effect after L-Dopa treatment by an inhibitor of Mao-B, deprenil

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Evidence for retrograde axonal transport of MPP+ in the rat.

29 October 2022

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Pargyline and deprenyl prevent the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in monkeys

29 October 2022

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Deprenyl suppresses the oxidant stress associated with increased dopamine turnover

29 October 2022

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MPTP-treated young mice but not aging mice show partial recovery of the nigrostriatal dopaminergic system by stereotaxic injection of acidic fibroblast growth factor (aFGF)

29 October 2022

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Involvement of monoamine oxidase enzymes in the action of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine, a selective neurotoxin, in the squirrel monkey: binding and biochemical studies

29 October 2022

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Increased dopamine synthesis in aging substantia nigra neurons

29 October 2022

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Gangliosides prevent MPTP toxicity in mice--an immunocytochemical study

29 October 2022

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Administration of GM1 ganglioside restores the dopamine content in striatum after chronic treatment with MPTP.

29 October 2022

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Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors

29 October 2022

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Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

29 October 2022

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Differences in the metabolism of MPTP in the rodent and primate parallel differences in sensitivity to its neurotoxic effects

29 October 2022

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The striatal dopamine dependency of life span in male rats. Longevity study with (-)deprenyl

29 October 2022

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Clinical neuromythology IX. Pyramid sale in the bucket shop: DATATOP bottoms out

29 October 2022

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Pargyline Prevents MPTP-Induced Parkinsonism in Primates

29 October 2022

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Urinary excretion of MPTP and its primary metabolites in mice

29 October 2022

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Acute ultrastructural and behavioral effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice

29 October 2022

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Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

29 October 2022

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Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain

29 October 2022

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Inhibition of ATP synthesis by 1-methyl-4-phenylpyridinium ion (MPP+) in isolated mitochondria from mouse brains

29 October 2022

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Inhibition of mitochondrial respiration by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mouse brain in vivo

29 October 2022

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Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

29 October 2022

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DATATOP: a multicenter controlled clinical trial in early Parkinson's disease. Parkinson Study Group

29 October 2022

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2-Phenylethylamine: a modulator of catecholamine transmission in the mammalian central nervous system?

29 October 2022

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Specificity of antisera prepared against pure bovine MAO-B.

29 October 2022

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Comparative morphology of the substantia nigra and ventral tegmental area in the monkey, cat and rat.

29 October 2022

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Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP.

29 October 2022

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Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism

29 October 2022

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The inhibition site of MPP+, the neurotoxic bioactivation product of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase

29 October 2022

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Astrocytes convert the parkinsonism inducing neurotoxin, MPTP, to its active metabolite, MPP+

29 October 2022

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Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy.

29 October 2022

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Dose-dependent destruction of the coeruleus-cortical and nigral-striatal projections by MPTP.

29 October 2022

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Metabolism of [14C]MPTP in mouse and monkey implicates MPP+, and not bound metabolites, as the operative neurotoxin

29 October 2022

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Astroglial ablation prevents MPTP-induced nigrostriatal neuronal death

29 October 2022

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MPTP produces reversible disappearance of tyrosine hydroxylase-containing retinal amacrine cells

29 October 2022

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The effect of deprenyl (selegiline) on the natural history of Parkinson's disease

29 October 2022

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Effect of deprenyl on the progression of disability in early Parkinson's disease

29 October 2022

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Is there a non-dopaminergic nigrostriatal pathway?

29 October 2022

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Histochemical localization of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine oxidation in the mouse brain

29 October 2022

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Distinct monoamine oxidase A and B populations in primate brain

29 October 2022

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Localization of distinct monoamine oxidase a and monoamine oxidase b cell populations in human brainstem

29 October 2022

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29 October 2022

Identifiers

1 reference

13 February 2018

1 reference

13 February 2018