The p53 family: guardians of maternal reproduction (Q48678761)

14 February 2018

review article

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title

The p53 family: guardians of maternal reproduction (English)

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14 February 2018

author name string

Arnold J Levine

1

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14 February 2018

Richard Tomasini

2

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14 February 2018

Frank D McKeon

3

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14 February 2018

Tak W Mak

4

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14 February 2018

Gerry Melino

5

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14 February 2018

publication date

1 April 2011

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14 February 2018

Nature Reviews Molecular Cell Biology

published in

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14 February 2018

volume

12

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14 February 2018

issue

4

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14 February 2018

page(s)

259-265

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14 February 2018

The p53 orchestra: Mdm2 and Mdmx set the tone

cites work

1 reference

The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein

31 March 2020

1 reference

31 March 2020

1 reference

p63 and p73, the ancestors of p53.

31 March 2020

1 reference

p53 in health and disease

31 March 2020

1 reference

Transcriptional control of human p53-regulated genes

31 March 2020

1 reference

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

31 March 2020

2 references

https://pubmed.ncbi.nlm.nih.gov/21427767

31 March 2020

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

1 reference

Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway

31 March 2020

1 reference

On the shoulders of giants: p63, p73 and the rise of p53.

31 March 2020

1 reference

Structural basis for gene activation by p53 family members

31 March 2020

1 reference

Regulation of p53 family members by the ubiquitin-like SUMO system

31 March 2020

1 reference

The impact of p53 and p73 on aneuploidy and cancer

31 March 2020

1 reference

p63 Is essential for the proliferative potential of stem cells in stratified epithelia

31 March 2020

1 reference

DeltaNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2.

31 March 2020

1 reference

p63: the phantom of the tumor suppressor

31 March 2020

1 reference

p53 regulates hematopoietic stem cell quiescence.

31 March 2020

1 reference

p53 is a suppressor of inflammatory response in mice.

31 March 2020

1 reference

Tumor protein 53-induced nuclear protein 1 is a major mediator of p53 antioxidant function

31 March 2020

1 reference

Running on empty: how p53 controls INS/IGF signaling and affects life span

31 March 2020

1 reference

The origins and evolution of the p53 family of genes

31 March 2020

1 reference

One billion years of p53/p63/p73 evolution

31 March 2020

1 reference

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

31 March 2020

1 reference

p63 is a p53 homologue required for limb and epidermal morphogenesis

31 March 2020

1 reference

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

31 March 2020

1 reference

TAp63 prevents premature aging by promoting adult stem cell maintenance

31 March 2020

1 reference

p63 protects the female germ line during meiotic arrest

31 March 2020

1 reference

Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death

31 March 2020

1 reference

p53 regulates maternal reproduction through LIF

31 March 2020

1 reference

p63 null mutation protects mouse oocytes from radio-induced apoptosis

31 March 2020

1 reference

Preserving fertility during cancer treatment

31 March 2020

1 reference

The pachytene checkpoint and its relationship to evolutionary patterns of polyploidization and hybrid sterility

31 March 2020

1 reference

Sex ratio and unisexual sterility in hybrid animals

31 March 2020

1 reference

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

31 March 2020

1 reference

T antigen is bound to a host protein in SY40-transformed cells

31 March 2020

1 reference

Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse

31 March 2020

1 reference

The p53 proto-oncogene can act as a suppressor of transformation

31 March 2020

1 reference

Translocation of the p53 gene in t(15;17) in acute promyelocytic leukaemia

31 March 2020

1 reference

Genetic mechanisms of tumor suppression by the human p53 gene

31 March 2020

1 reference

p53: a new player in reproduction

31 March 2020

1 reference

The role of p53 gene family in reproduction

31 March 2020

1 reference

TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity

31 March 2020

1 reference

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice

31 March 2020

1 reference

Heterozygosity for a Bub1 mutation causes female-specific germ cell aneuploidy in mice.

31 March 2020

1 reference

Aurora kinase B modulates chromosome alignment in mouse oocytes

31 March 2020

1 reference

Intrabursal injection of clodronate liposomes causes macrophage depletion and inhibits ovulation in the mouse ovary

31 March 2020

1 reference

Macrophage contributions to ovarian function.

31 March 2020

1 reference

p53 tumour suppressor gene polymorphism is associated with recurrent implantation failure.

31 March 2020

1 reference

Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans

31 March 2020

1 reference

Natural selection and functional genetic variation in the p53 pathway

31 March 2020

1 reference

DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer

31 March 2020

1 reference

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

31 March 2020

1 reference

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

31 March 2020

1 reference

The p53 family in differentiation and tumorigenesis.

31 March 2020

1 reference

P73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis

31 March 2020

1 reference

p53 is cleaved by caspases generating fragments localizing to mitochondria

31 March 2020

1 reference

P63 and P73: P53 mimics, menaces and more

31 March 2020

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Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor

31 March 2020

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Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death

31 March 2020

1 reference

p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence

31 March 2020

1 reference

Simian Virus 40 Activates ATR-Δp53 Signaling To Override Cell Cycle and DNA Replication Control

31 March 2020

1 reference

Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph disease

31 March 2020

1 reference

TAp63 and DeltaNp63 in cancer and epidermal development

31 March 2020

1 reference

Regulation of ovulation rate in mammals: contribution of sheep genetic models

31 March 2020

1 reference

Oocyte-specific deletion of Pten in mice reveals a stage-specific function of PTEN/PI3K signaling in oocytes in controlling follicular activation

31 March 2020

1 reference

PDK1 signaling in oocytes controls reproductive aging and lifespan by manipulating the survival of primordial follicles.

31 March 2020

1 reference

NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression

31 March 2020

1 reference

Female mice haploinsufficient for an inactivated androgen receptor (AR) exhibit age-dependent defects that resemble the AR null phenotype of dysfunctional late follicle development, ovulation, and fertility.

31 March 2020

1 reference

Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles

31 March 2020

1 reference

Subfertility caused by altered follicular development and oocyte growth in female mice lacking PKB alpha/Akt1.

31 March 2020

1 reference

DeltaNp63 is essential for epidermal commitment of embryonic stem cells.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21427767

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRM3086

1 reference

14 February 2018

1 reference

14 February 2018