Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A a (Q40000258)

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scientific article published on February 15, 1976

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English	Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A a	scientific article published on February 15, 1976

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16 September 2017

Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A a (English)

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16 September 2017

Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A and reduced and oxidized nicotinamide-adenine dinucleotide (English)

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10.1042/BJ1540327

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24 December 2022

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A. L. Kerbey

1

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24 December 2022

P. J. Randle

2

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24 December 2022

R. H. Cooper

3

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24 December 2022

S. Whitehouse

4

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H. T. Pask

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24 December 2022

R. M. Denton

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24 December 2022

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1 February 1976

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16 September 2017

15 February 1976

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24 December 2022

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/180974/?tool=EBI

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24 December 2022

https://europepmc.org/articles/PMC1172714

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24 December 2022

https://europepmc.org/articles/PMC1172714?pdf=render

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online access status

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Europe PubMed Central

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24 December 2022

https://portlandpress.com/biochemj/article-pdf/154/2/327/781753/bj1540327.pdf

Portable Document Format

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10.1042/BJ1540327

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24 December 2022

Biochemical Journal

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16 September 2017

154

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Europe PubMed Central

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16 September 2017

2

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16 September 2017

327-348

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16 September 2017

BIOLOGICAL OXIDOREDUCTIONS.

1 reference

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22 September 2017

The enzymatic acetylation of amines.

1 reference

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22 September 2017

Measurement of flow of carbon atoms from glucose and glycogen glucose to glyceride glycerol and glycerol in rat heart and epididymal adipose tissue. Effects of insulin, adrenaline and alloxan-diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

22 September 2017

Concentrations of glycerides and phospholipids in rat heart and gastrocnemius muscles. Effects of alloxan-diabetes and perfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

22 September 2017

Interactions of Metabolism and the Physiological Role of Insulin

1 reference

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22 September 2017

The coupling between energy-yielding and energy-utilizing reactions in mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

22 September 2017

Effects of dichloroacetate on the metabolism of glucose, pyruvate, acetate, 3-hydroxybutyrate and palmitate in rat diaphragm and heart muscle in vitro and on extraction of glucose, lactate, pyruvate and free fatty acids by dog heart in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

22 September 2017

-Keto acid dehydrogenase complexes. XV. Purification and properties of the component enzymes of the pyruvate dehydrogenase complexes from bovine kidney and heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

22 September 2017

Calcium ions and the regulation of pyruvate dehydrogenase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

22 September 2017

Recent advances in glycogen metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

22 September 2017

Alpha-keto acid dehydrogenase complexes. XI. Comparative studies of regulatory properties of the pyruvate dehydrogenase complexes from kidney, heart, and liver mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

22 September 2017

Alpha-keto acid dehydrogenase complexes. X. Regulation of the activity of the pyruvate dehydrogenase complex from beef kidney mitochondria by phosphorylation and dephosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

22 September 2017

The mitochondrial pyruvate carrier. Kinetics and specificity for substrates and inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

22 September 2017

Exchangeable and total calcium pools in mitochondria of rat epididymal fat-pads and isolated fat-cells. Role in the regulation of pyruvate dehydrogenase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

22 September 2017

Regulation of pyruvate dehydrogenase kinase and phosphatase by acetyl-CoA/CoA and NADH/NAD ratios

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

22 September 2017

Control of pyruvate dehydrogenase activity in intact cardiac mitochondria. Regulation of the inactivation and activation of the dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

22 September 2017

Regulation of pyruvate dehydrogenase and pyruvate dehydrogenase phosphate phosphatase activity in rat epididymal fat-pads. Effects of starvation, alloxan-diabetes and high-fat diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

22 September 2017

Control of the tricarboxylate cycle and its interactions with glycolysis during acetate utilization in rat heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Regulation of adipose tissue pyruvate dehydrogenase by insulin and other hormones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Regulation of pyruvate-dehydrogenase interconversion in rat-liver mitochondria as related to the phosphorylation state of intramitochondrial adenine nucleotides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Mechanisms regulating adipose-tissue pyruvate dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Mechanism of activation of pyruvate dehydrogenase by dichloroacetate and other halogenated carboxylic acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Regulation of heart muscle pyruvate dehydrogenase kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Amino acid sequence of a (32P) phosphopeptide from pig liver pyruvate kinase phosphorylated by cyclic 3',5'-AMP-stimulated protein kinase and gamma-(32P)ATP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Calcium and magnesium ions as effectors of adipose-tissue pyruvate dehydrogenase phosphate phosphatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Alpha-keto acid dehydrogenase complexes. XX. A kinetic study of the pyruvate dehydrogenase complex from bovine kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Stimulation by calcium ions of pyruvate dehydrogenase phosphate phosphatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Active and inactive forms of pyruvate dehydrogenase in rat heart and kidney: effect of diabetes, fasting, and refeeding on pyruvate dehydrogenase interconversion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Pyruvate dehydrogenase, substrate specificity and product inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Use of the liquid scintillation spectrometer for determining adenosine triphosphate by the luciferase enzyme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Regulation of glucose uptake by muscle. 9. Effects of fatty acids and ketone bodies, and of alloxan-diabetes and starvation, on pyruvate metabolism and on lactate-pyruvate and L-glycerol 3-phosphate-dihydroxyacetone phosphate concentration ratios in

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Regulation of pyruvate dehydrogenase in isolated rat liver mitochondria. Effects of octanoate, oxidation-reduction state, and adenosine triphosphate to adenosine diphosphate ratio

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

17 June 2018

Activation of pyruvate dehydrogenase in perfused rat heart by dichloroacetate (Short Communication).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

20 August 2018

Pyruvate metabolism in the perfused rat heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

20 August 2018

Regulation of glucose uptake by muscles. 10. Effects of alloxan-diabetes, starvation, hypophysectomy and adrenalectomy, and of fatty acids, ketone bodies and pyruvate, on the glycerol output and concentrations of free fatty acids, long-chain fatty a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1172714

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A simple method for the preparation of 32P-labelled adenosine triphosphate of high specific activity

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20 August 2018

GLYCOLYTIC CONTROL MECHANISMS. I. INHIBITION OF GLYCOLYSIS BY ACETATE AND PYRUVATE IN THE ISOLATED, PERFUSED RAT HEART

1 reference

https://pubmed.ncbi.nlm.nih.gov/180974

12 December 2020

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BIOSYNTHESIS OF ACETOIN IN PIG HEART MUSCLE

1 reference

https://pubmed.ncbi.nlm.nih.gov/180974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/180974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of acylcarnitines and pyruvate as substrates for rat-liver mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/180974

12 December 2020

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Studies on the Properties of (-)-2-alpha-Hydroxyethyl-Thiamine Pyrophosphate ("Active Acetaldehyde")

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https://pubmed.ncbi.nlm.nih.gov/180974

12 December 2020

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Activation of Pyruvate Dehydrogenase during Metabolism of Ammonium Ions in Hemoglobin‐Free Perfused Rat Liver

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https://pubmed.ncbi.nlm.nih.gov/180974

12 December 2020

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Regulation of glutamate metabolism and interactions with the citric acid cycle in rat heart mitochondria

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Carnitine in intermediary metabolism. The metabolism of fatty acid esters of carnitine by mitochondria

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Removal of fatty acids from serum albumin by charcoal treatment

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https://pubmed.ncbi.nlm.nih.gov/180974

12 December 2020

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Regulation of Pyruvate Dehydrogenase in Rat Liver Mitochondria by Phosphorylation-Dephosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/180974

12 December 2020

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An energy-dependent transformation of a ferricytochrome of the mitochondrial respiratory chain

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A fluorimetric method for the quantitative microanalysis of adenine and pyridine nucleotides

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ATP controlled redox states of respiratory carriers under the influence of DPNH-hydrogen accepting substrates

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Interconversion of pyruvate dehydrogenase in rat heart muscle upon perfusion with fatty acids or ketone bodies

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https://pubmed.ncbi.nlm.nih.gov/180974

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Determination of subpicomole levels of NADH and FMN using bacterial luciferase and the liquid scintillation spectrometer

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Effects of diabetes, fatty acids, and ketone bodies on tricarboxylic acid cycle metabolism in the perfused rat heart

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https://pubmed.ncbi.nlm.nih.gov/180974

12 December 2020

based on heuristic

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Regulation of hepatic acetyl coenzyme A carboxylase by phosphorylation and dephosphorylation

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https://pubmed.ncbi.nlm.nih.gov/180974

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Kinetic and regulatory properties of heart muscle pyruvate dehydrogenase

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https://pubmed.ncbi.nlm.nih.gov/180974

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ1540327

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Europe PubMed Central

PMC publication ID

16 September 2017

release_uh3wc22twngbdav73f7wh6gqba

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24 November 2022

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

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