CNS delivery of vectored prion-specific single-chain antibodies delays disease onset (Q40027533)

16 September 2017

title

CNS delivery of vectored prion-specific single-chain antibodies delays disease onset (English)

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16 September 2017

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Charles A Wuertzer

1

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16 September 2017

Mark A Sullivan

series ordinal

2

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16 September 2017

Xing Qiu

series ordinal

3

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16 September 2017

Howard J Federoff

series ordinal

4

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16 September 2017

publication date

8 January 2008

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16 September 2017

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16 September 2017

volume

16

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16 September 2017

issue

3

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16 September 2017

page(s)

481-486

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Specific binding of normal prion protein to the scrapie form via a localized domain initiates its conversion to the protease-resistant state

16 September 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Immunization delays the onset of prion disease in mice.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Immunisation with a synthetic prion protein-derived peptide prolongs survival times of mice orally exposed to the scrapie agent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Prevention of scrapie pathogenesis by transgenic expression of anti-prion protein antibodies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Monoclonal antibodies inhibit prion replication and delay the development of prion disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Cross-Linking Cellular Prion Protein Triggers Neuronal Apoptosis in Vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Paracrine inhibition of prion propagation by anti-PrP single-chain Fv miniantibodies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Analysis of antibody selection by phage display utilizing anti-phenobarbital antibodies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Recombinant human antibody single chain variable fragments reactive with Candida albicans surface antigens

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Humoral immune response to native eukaryotic prion protein correlates with anti-prion protection.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Early spread of scrapie from the gastrointestinal tract to the central nervous system involves autonomic fibers of the splanchnic and vagus nerves

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Variant Creutzfeldt-jakob disease: between lymphoid organs and brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Adeno-associated viral vector-mediated ApoE expression in Alzheimer's disease mice: low CNS immune response, long-term expression, and astrocyte specificity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Immune responses to AAV in a phase I study for Canavan disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

The immunogenicity of intracerebral virus infection depends on anatomical site.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Novel vectors for the expression of antibody molecules using variable regions generated by polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Identification of a gene which controls the incubation period of some strains of scrapie agent in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Regional mapping of prion proteins in brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300387

7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300387

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16 September 2017

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