Ectopic TAL-1/SCL expression in phenotypically normal or leukemic myeloid precursors: proliferative and antiapoptotic effects coupled with a differentiation blockade (Q40022237)

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scientific article published on May 1997

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English	Ectopic TAL-1/SCL expression in phenotypically normal or leukemic myeloid precursors: proliferative and antiapoptotic effects coupled with a differentiation blockade	scientific article published on May 1997

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scholarly article

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Europe PubMed Central

PMC publication ID

16 September 2017

Ectopic TAL-1/SCL expression in phenotypically normal or leukemic myeloid precursors: proliferative and antiapoptotic effects coupled with a differentiation blockade (English)

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Europe PubMed Central

PMC publication ID

16 September 2017

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Carlo Maria Croce

8

object named as

Croce CM

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16 September 2017

author name string

Condorelli GL

1

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16 September 2017

Tocci A

2

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16 September 2017

Botta R

3

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16 September 2017

Facchiano F

4

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16 September 2017

Testa U

5

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Europe PubMed Central

PMC publication ID

16 September 2017

Vitelli L

6

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16 September 2017

Valtieri M

7

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16 September 2017

Peschle C

9

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16 September 2017

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publication date

1 May 1997

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16 September 2017

Molecular and Cellular Biology

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16 September 2017

17

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Europe PubMed Central

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16 September 2017

5

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Europe PubMed Central

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16 September 2017

2954-2969

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Europe PubMed Central

PMC publication ID

16 September 2017

The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse

1 reference

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1 reference

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Wild-type p53 induces diverse effects in 32D cells expressing different oncogenes.

1 reference

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The SCL gene product is regulated by and differentially regulates cytokine responses during myeloid leukemic cell differentiation

1 reference

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22 September 2017

Preferred sequences for DNA recognition by the TAL1 helix-loop-helix proteins

1 reference

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Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells

1 reference

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TAL1, TAL2 and LYL1: a family of basic helix-loop-helix proteins implicated in T cell acute leukaemia

1 reference

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22 September 2017

The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis.

1 reference

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The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells

1 reference

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Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

1 reference

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Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia

1 reference

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Expression of TAL-1 proteins in human tissues

1 reference

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1 reference

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Loss of TAL-1 protein activity induces premature apoptosis of Jurkat leukemic T cells upon medium depletion

1 reference

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Expression of tal-1 and GATA-binding proteins during human hematopoiesis

1 reference

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Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene

1 reference

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Coordinate expression and developmental role of Id2 protein and TAL1/E2A heterodimer in erythroid progenitor differentiation.

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Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells

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Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma

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Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript

1 reference

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The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein

1 reference

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Site-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemia

1 reference

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Enhancer-binding activity of the tal-1 oncoprotein in association with the E47/E12 helix-loop-helix proteins

1 reference

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1 reference

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Antisense SCL suppresses self-renewal and enhances spontaneous erythroid differentiation of the human leukaemic cell line K562.

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A third tal-1 promoter is specifically used in human T cell leukemias

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The SCL gene product: a positive regulator of erythroid differentiation

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Opposing effects of the basic helix-loop-helix transcription factor SCL on erythroid and monocytic differentiation

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Reconstitution of mice with bone marrow cells expressing the SCL gene is insufficient to cause leukemia

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Does activation of the TAL1 gene occur in a majority of patients with T-cell acute lymphoblastic leukemia? A pediatric oncology group study

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The expression pattern of erythrocyte/megakaryocyte-related transcription factors GATA-1 and the stem cell leukemia gene correlates with hematopoietic differentiation and is associated with outcome of acute myeloid leukemia

1 reference

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The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages

1 reference

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T-cell-directed TAL-1 expression induces T-cell malignancies in transgenic mice

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Retroviral vector design for long-term expression in murine hematopoietic cells in vivo

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Identifiers

10.1128/MCB.17.5.2954

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 September 2017

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