Herpes simplex virus transactivator ICP4 operationally substitutes for the cellular transcription factor Sp1 for efficient expression of the viral thymidine kinase gene (Q40058856)

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scientific article published on February 1, 1991

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English	Herpes simplex virus transactivator ICP4 operationally substitutes for the cellular transcription factor Sp1 for efficient expression of the viral thymidine kinase gene	scientific article published on February 1, 1991

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1846184%20AND%20SRC:MED&resulttype=core&format=json

19 September 2019

Herpes simplex virus transactivator ICP4 operationally substitutes for the cellular transcription factor Sp1 for efficient expression of the viral thymidine kinase gene (English)

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19 September 2019

immediate-early proteins

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8 December 2022

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8 December 2022

1 reference

10.1128/JVI.65.2.565-574.1991

https://api.crossref.org/works/10.1128/JVI.65.2.565-574.1991

8 December 2022

1 reference

10.1128/JVI.65.2.565-574.1991

https://api.crossref.org/works/10.1128/JVI.65.2.565-574.1991

8 December 2022

author name string

A. N. Imbalzano

1

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8 December 2022

D. M. Coen

2

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8 December 2022

N. A. DeLuca

3

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8 December 2022

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1 February 1991

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19 September 2019

full work available at URL

http://jvi.asm.org/cgi/content/abstract/65/2/565

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8 December 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1846184/?tool=EBI

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8 December 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1846184/pdf/?tool=EBI

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8 December 2022

https://europepmc.org/articles/PMC239793

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8 December 2022

https://europepmc.org/articles/PMC239793?pdf=render

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Europe PubMed Central

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8 December 2022

https://journals.asm.org/doi/pdf/10.1128/jvi.65.2.565-574.1991

1 reference

10.1128/JVI.65.2.565-574.1991

https://api.crossref.org/works/10.1128/JVI.65.2.565-574.1991

8 December 2022

Journal of Virology

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19 September 2019

65

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19 September 2019

2

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19 September 2019

565-574

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1846184%20AND%20SRC:MED&resulttype=core&format=json

19 September 2019

Multiple factors required for accurate initiation of transcription by purified RNA polymerase II.

1 reference

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Eukaryotic gene transcription with purified components

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Effects of deletions on expression of the herpes simplex virus thymidine kinase gene from the intact viral genome: the amino terminus of the enzyme is dispensable for catalytic activity

1 reference

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22 September 2017

Transcription of herpes simplex virus genes in vivo: overlap of a late promoter with the 3' end of the early thymidine kinase gene

1 reference

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22 September 2017

Regulation of α genes of herpes simplex virus: Expression of chimeric genes produced by fusion of thymidine kinase with α gene promoters

1 reference

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22 September 2017

Fine-structure mapping and functional analysis of temperature-sensitive mutants in the gene encoding the herpes simplex virus type 1 immediate early protein VP175

1 reference

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22 September 2017

Transcriptional and genetic analyses of the herpes simplex virus type 1 genome: coordinates 0.29 to 0.45

1 reference

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22 September 2017

Temperature-sensitive mutants in herpes simplex virus type 1 ICP4 permissive for early gene expression

1 reference

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A new technique for the assay of infectivity of human adenovirus 5 DNA

1 reference

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22 September 2017

Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins

1 reference

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22 September 2017

Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay

1 reference

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22 September 2017

Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Binding of the herpes simplex virus immediate-early gene product ICP4 to its own transcription start site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Mapping of the transcriptional initiation site of the herpes simplex virus type 1 ICP8 gene in infected and transfected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Transcriptional control signals of a herpes simplex virus type 1 late (gamma 2) gene lie within bases -34 to +124 relative to the 5' terminus of the mRNA

1 reference

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22 September 2017

The control of herpes simplex virus type-1 late gene transcription: a 'TATA-box'/cap site region is sufficient for fully efficient regulated activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Association of the herpes simplex virus regulatory protein ICP4 with specific nucleotide sequences in DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Activation of immediate-early, early, and late promoters by temperature-sensitive and wild-type forms of herpes simplex virus type 1 protein ICP4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Promoter domains required for expression of plasmid-borne copies of the herpes simplex virus thymidine kinase gene in virus-infected mouse fibroblasts and microinjected frog oocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Alpha 4, the major regulatory protein of herpes simplex virus type 1, is stably and specifically associated with promoter-regulatory domains of alpha genes and of selected other viral genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Identification of immediate early genes from herpes simplex virus that transactivate the virus thymidine kinase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Isolation of herpes simplex virus regulatory protein ICP4 as a homodimeric complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Evidence for a direct role for both the 175,000- and 110,000-molecular-weight immediate-early proteins of herpes simplex virus in the transactivation of delayed-early promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Accumulation of herpes simplex virus type 1 RNAs of different kinetic classes in the cytoplasm of infected cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

The regions of the herpes simplex virus type 1 immediate early protein Vmw175 required for site specific DNA binding closely correspond to those involved in transcriptional regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Eukaryotic transcriptional regulatory proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

22 September 2017

Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins

1 reference

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22 September 2017

Examination of the roles of transcription factor Sp1-binding sites and an octamer motif in trans induction of the herpes simplex virus thymidine kinase gene

1 reference

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DNA nucleotide sequence analysis of the immediate-early gene of pseudorabies virus

1 reference

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Delineation of regulatory domains of early (beta) and late (gamma 2) genes by construction of chimeric genes expressed in herpes simplex virus 1 genomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=239793

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ICP4-binding sites in the promoter and coding regions of the herpes simplex virus gD gene contribute to activation of in vitro transcription by ICP4

1 reference

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Functional domains and upstream activation properties of cloned human TATA binding protein

1 reference

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Mechanism of transcriptional activation by Sp1: evidence for coactivators

1 reference

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Functional relevance of specific interactions between herpes simplex virus type 1 ICP4 and sequences from the promoter-regulatory domain of the viral thymidine kinase gene

1 reference

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Transcriptional activation by Sp1 as directed through TATA or initiator: specific requirement for mammalian transcription factor IID

1 reference

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The adenovirus E4 17-kilodalton protein complexes with the cellular transcription factor E2F, altering its DNA-binding properties and stimulating E1A-independent accumulation of E2 mRNA.

1 reference

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Detection of specific sequences among DNA fragments separated by gel electrophoresis

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Nucleotide sequence of the rightward operator of phage lambda

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Abnormal properties of an immediate early polypeptide in cells infected with the herpes simplex virus type 1 mutant tsK

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Evidence for a herpes simplex virus-specific factor controlling the transcription of deoxypyrimidine kinase

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Thymidine kinase activity of biochemically transformed mouse cells after superinfection by thymidine kinase-negative, temperature-sensitive, herpes simplex virus mutants

1 reference

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Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides

1 reference

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Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: Identification of an upstream control region

1 reference

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A herpes simplex virus type 1 function continuously required for early and late virus RNA synthesis

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Factors involved in specific transcription by mammalian RNA polymerase II. RNA polymerase II-associating protein 30 is an essential component of transcription factor IIF.

1 reference

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Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro

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A specific 15-bp TATA box promoter element is required for expression of a herpes simplex virus type 1 late gene

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Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

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https://pubmed.ncbi.nlm.nih.gov/1846184

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based on heuristic

inferred from PubMed ID database lookup

A TATA box implicated in E1A transcriptional activation of a simple adenovirus 2 promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/1846184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational dissection of the HSV-1 immediate-early protein Vmw175 involved in transcriptional transactivation and repression

1 reference

https://pubmed.ncbi.nlm.nih.gov/1846184

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.65.2.565-574.1991

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1846184

8 December 2022

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1846184%20AND%20SRC:MED&resulttype=core&format=json

19 September 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1846184%20AND%20SRC:MED&resulttype=core&format=json

19 September 2019

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