MLH1- and ATM-dependent MAPK signaling is activated through c-Abl in response to the alkylator N-methyl-N'-nitro-N'-nitrosoguanidine (Q40084513)

17 September 2017

title

MLH1- and ATM-dependent MAPK signaling is activated through c-Abl in response to the alkylator N-methyl-N'-nitro-N'-nitrosoguanidine (English)

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17 September 2017

Wan-Ju Kim

1

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17 September 2017

Baskaran Rajasekaran

series ordinal

2

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17 September 2017

Kevin D Brown

series ordinal

3

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17 September 2017

language of work or name

English

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publication date

5 September 2007

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Journal of Biological Chemistry

17 September 2017

number of pages

11

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based on heuristic

inferred from page(s)

published in

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17 September 2017

volume

282

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17 September 2017

issue

44

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17 September 2017

page(s)

32021-32031

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Checkpoints: controls that ensure the order of cell cycle events

17 September 2017

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ATM is activated in response to N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA alkylation

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Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase

21 January 2018

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MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation

21 January 2018

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The mismatch repair system is required for S-phase checkpoint activation

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The p38 Mitogen-Activated Protein Kinase Pathway Links the DNA Mismatch Repair System to the G2 Checkpoint and to Resistance to Chemotherapeutic DNA-Methylating Agents

21 January 2018

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c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation

21 January 2018

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The monofunctional alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine triggers apoptosis through p53-dependent and -independent pathways.

21 January 2018

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Apoptosis induced by MNNG in human TK6 lymphoblastoid cells is p53 and Fas/CD95/Apo-1 related

21 January 2018

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Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

21 January 2018

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c-Jun-dependent CD95-L expression is a rate-limiting step in the induction of apoptosis by alkylating agents

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M701451200

1 reference

17 September 2017

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