Targeting phospho-Ser422 by active Tau Immunotherapy in the THYTau22 mouse model: a suitable therapeutic approach (Q40141995)

17 September 2017

Targeting phospho-Ser422 by active Tau Immunotherapy in the THYTau22 mouse model: a suitable therapeutic approach (English)

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17 September 2017

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Susanna Schraen-Maschke

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object named as

Susanna Schraen-Maschke

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author name string

Laetitia Troquier

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17 September 2017

Raphaelle Caillierez

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17 September 2017

Sylvie Burnouf

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17 September 2017

Francisco J Fernandez-Gomez

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17 September 2017

Marie-Eve Grosjean

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17 September 2017

Nadege Zommer

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17 September 2017

Nicolas Sergeant

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17 September 2017

Susanna Schraen-Maschke

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17 September 2017

David Blum

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17 September 2017

Luc Buee

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17 September 2017

1 May 2012

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Current Alzheimer Research

17 September 2017

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17 September 2017

9

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17 September 2017

4

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17 September 2017

397-405

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describes a project that uses

17 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3637173/fullTextXML

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22 September 2017

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22 September 2017

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Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer's disease.

22 September 2017

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Extracellular tau is toxic to neuronal cells.

22 September 2017

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Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits

22 September 2017

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22 September 2017

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Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility

22 September 2017

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

22 September 2017

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Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau.

22 September 2017

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Active versus passive immunization against hepatitis A in the Israel defence forces: a cost-benefit analysis

22 September 2017

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Induction of a specific tau Alzheimer epitope in SY-5Y neuroblastoma cells.

25 September 2017

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C-terminal truncation modulates both nucleation and extension phases of tau fibrillization

25 September 2017

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Phosphorylated serine422 on tau proteins is a pathological epitope found in several diseases with neurofibrillary degeneration

15 June 2018

1 reference

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A conformation- and phosphorylation-dependent antibody recognizing the paired helical filaments of Alzheimer's disease.

15 June 2018

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Characterization of mAb AP422, a novel phosphorylation-dependent monoclonal antibody against tau protein

15 June 2018

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Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology.

15 June 2018

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Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission.

20 August 2018

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Efficacy and safety of immunization with phosphorylated tau against neurofibrillary tangles in mice

20 August 2018

1 reference

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Phosphorylation of Tau at S422 is enhanced by Abeta in TauPS2APP triple transgenic mice.

20 August 2018

1 reference

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Divergent phosphorylation pattern of tau in P301L tau transgenic mice

20 August 2018

1 reference

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Tauopathy-like abnormalities and neurologic deficits in mice immunized with neuronal tau protein

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3637173

Pseudophosphorylation of tau at serine 422 inhibits caspase cleavage: in vitro evidence and implications for tangle formation in vivo.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3637173

Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3637173

Primary progressive aphasia as the initial manifestation of corticobasal degeneration and unusual tauopathies.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3637173

Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3637173

Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3637173

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3637173

Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's disease.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3637173

Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer's disease.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3637173

Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases in intact cells

20 August 2018

1 reference

12 December 2020

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

1 reference

12 December 2020

Ubiquitin-negative mini-pick-like bodies in the dentate gyrus in p301l tauopathy

1 reference

12 December 2020

Intra-peritoneal injection of polyclonal anti-interferon alpha antibodies cross the blood brain barrier and neutralize interferon alpha

1 reference

12 December 2020

Mechanisms of A beta plaque clearance following passive A beta immunization

1 reference

12 December 2020

10.2174/156720512800492503

Identifiers

DOI

1 reference

17 September 2017

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17 September 2017

PubMed publication ID

22272619

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