Ras/ERK1/2-mediated STAT3 Ser727 phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation. (Q40185668)

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scientific article published on 5 January 2007

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English	Ras/ERK1/2-mediated STAT3 Ser727 phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation.	scientific article published on 5 January 2007

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23 December 2019

Ras/ERK1/2-mediated STAT3 Ser727 phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation (English)

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23 December 2019

phosphorylation

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23 December 2019

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23 December 2019

Charles H C M Buys

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Charles H C M Buys

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23 December 2019

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Iván Plaza-Menacho

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23 December 2019

Tineke van der Sluis

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23 December 2019

Harry Hollema

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23 December 2019

Oliver Gimm

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23 December 2019

Anthony I Magee

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23 December 2019

Bart J L Eggen

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5 January 2007

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23 December 2019

Journal of Biological Chemistry

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23 December 2019

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23 December 2019

6415-6424

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23 December 2019

GDNF family neurotrophic factor signaling: four masters, one servant?

1 reference

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21 January 2018

RET as a diagnostic and therapeutic target in sporadic and hereditary endocrine tumors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

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Current concepts in RET-related genetics, signaling and therapeutics

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Central role of the threonine residue within the p+1 loop of receptor tyrosine kinase in STAT3 constitutive phosphorylation in metastatic cancer cells

1 reference

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21 January 2018

RET-familial medullary thyroid carcinoma mutants Y791F and S891A activate a Src/JAK/STAT3 pathway, independent of glial cell line-derived neurotrophic factor.

1 reference

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Transcriptional responses to polypeptide ligands: the JAK-STAT pathway

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STAT signaling in the pathogenesis and treatment of leukemias

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Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

Serine phosphorylation and negative regulation of Stat3 by JNK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M608952200

21 January 2018

STAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylation

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21 January 2018

Sequential activation of Rac-1, SEK-1/MKK-4, and protein kinase Cdelta is required for interleukin-6-induced STAT3 Ser-727 phosphorylation and transactivation

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21 January 2018

Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variant

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Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor

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21 January 2018

Cellular effects of imatinib on medullary thyroid cancer cells harboring multiple endocrine neoplasia Type 2A and 2B associated RET mutations

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21 January 2018

Evaluation of potential mechanisms underlying genotype-phenotype correlations in multiple endocrine neoplasia type 2.

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21 January 2018

Activation of signal transducer and activator of transcription 3 by oncogenic RET/PTC (rearranged in transformation/papillary thyroid carcinoma) tyrosine kinase: roles in specific gene regulation and cellular transformation

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21 January 2018

Pheochromocytoma and medullary thyroid carcinoma: a new genotype-phenotype correlation of the RET protooncogene 891 germline mutation.

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21 January 2018

The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling.

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21 January 2018

The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells

2 references

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1172/JCI200522758

30 December 2023

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