Alpha-crystallin is a target gene of the farnesoid X-activated receptor in human livers (Q40398568)

20 September 2017

title

Alpha-crystallin is a target gene of the farnesoid X-activated receptor in human livers (English)

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20 September 2017

Florence Y Lee

1

1 reference

20 September 2017

Heidi R Kast-Woelbern

2

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20 September 2017

Jenny Chang

3

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20 September 2017

Guizhen Luo

4

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20 September 2017

Stacey A Jones

5

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20 September 2017

Michael C Fishbein

6

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20 September 2017

Peter A Edwards

7

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20 September 2017

language of work or name

English

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publication date

11 July 2005

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Journal of Biological Chemistry

20 September 2017

published in

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20 September 2017

volume

280

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20 September 2017

issue

36

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20 September 2017

page(s)

31792-31800

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Alpha-crystallin as a molecular chaperone

20 September 2017

cites work

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21 January 2018

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The function of alpha-crystallin in vision

21 January 2018

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Immunoreactive alpha A crystallin in rat non-lenticular tissues detected with a sensitive immunoassay method

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alpha B subunit of lens-specific protein alpha-crystallin is present in other ocular and non-ocular tissues

21 January 2018

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Expression of the murine alpha B-crystallin gene is not restricted to the lens

21 January 2018

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Alpha-crystallin can function as a molecular chaperone

21 January 2018

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Alpha-crystallin/small heat shock protein has autokinase activity

21 January 2018

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Conversion from oligomers to tetramers enhances autophosphorylation by lens alpha A-crystallin. Specificity between alpha A- and alpha B-crystallin subunits.

21 January 2018

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Ultrastructural localization of alpha A-crystallin to the bovine lens fiber cell cytoskeleton

21 January 2018

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The beaded filament of the eye lens: an unexpected key to intermediate filament structure and function

21 January 2018

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Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA

21 January 2018

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Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21q

21 January 2018

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Alpha-B crystallin gene (CRYAB) mutation causes dominant congenital posterior polar cataract in humans

21 January 2018

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Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin

21 January 2018

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Nuclear receptors and the control of metabolism

21 January 2018

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Identification of a nuclear receptor that is activated by farnesol metabolites

21 January 2018

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Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation

21 January 2018

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Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters

21 January 2018

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Syndecan-1 expression is regulated in an isoform-specific manner by the farnesoid-X receptor

21 January 2018

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Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

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Identification of a nuclear receptor for bile acids

21 January 2018

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Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

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Enterohepatic bile salt transporters in normal physiology and liver disease

21 January 2018

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ABC transporter regulation by bile acids: where PXR meets FXR.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M503182200

Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M503182200

Prevention of cholesterol gallstone disease by FXR agonists in a mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Farnesoid X Receptor Activates Transcription of the Phospholipid Pump MDR3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Phosphatidylcholine translocase: a physiological role for the mdr2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Overview of chronic cholestatic conditions in adults: terminology and definitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

The pathology of cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Identification of a chemical tool for the orphan nuclear receptor FXR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

The C-terminal region of alpha-crystallin: involvement in protection against heat-induced denaturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Identification of PLTP as an LXR target gene and apoE as an FXR target gene reveals overlapping targets for the two nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Progenitor cells in diseased human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Liver fibrosis: from the bench to clinical targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

The farnesoid X receptor: a novel drug target?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Alternative RNA splicing of the murine alpha A-crystallin gene: protein-coding information within an intron

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

A pseudo-exon in the functional human alpha A-crystallin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Autoregulation of the human liver X receptor alpha promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

alpha-crystallin assists the renaturation of glyceraldehyde-3-phosphate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

The molecular chaperone, alpha-crystallin, inhibits amyloid formation by apolipoprotein C-II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: effects on amyloid fibril formation and chaperone activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Suppression of DTT-induced aggregation of abrin by alphaA- and alphaB-crystallins: a model aggregation assay for alpha-crystallin chaperone activity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

alphaA- and alphaB-crystallins protect glucose-6-phosphate dehydrogenase against UVB irradiation-induced inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

alphaB-crystallin exists as an independent protein in the heart and in the lens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Myofibrillar myopathy caused by novel dominant negative alpha B-crystallin mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Small heat shock protein alphaB-crystallin is part of cell cycle-dependent Golgi reorganization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Wound healing in the liver with particular reference to stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Hepatocellular transporters and cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

The continuing importance of bile acids in liver and intestinal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

Unfolding and refolding of a quinone oxidoreductase: alpha-crystallin, a molecular chaperone, assists its reactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503182200

21 January 2018

Identifiers

DOI

10.1074/JBC.M503182200

1 reference

release_r3l26fxqing7rghv7dg2imwpla

20 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/r3l26fxqing7rghv7dg2imwpla

mapped directly with Wikidata item

24 November 2022

based on heuristic

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