Production of fully human antibodies by transgenic mice (Q40425294)

20 September 2017

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title

Production of fully human antibodies by transgenic mice (English)

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20 September 2017

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A. Jakobovits

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7579668

21 May 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7579668

21 May 2024

publication date

1 October 1995

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full work available at URL

20 September 2017

https://api.elsevier.com/content/article/PII:095816699580093X?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0958-1669(95)80093-X

https://api.elsevier.com/content/article/PII:095816699580093X?httpAccept=text/plain

21 May 2024

1 reference

https://api.crossref.org/works/10.1016/0958-1669(95)80093-X

Current Opinion in Biotechnology

21 May 2024

published in

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20 September 2017

volume

6

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20 September 2017

issue

5

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20 September 2017

page(s)

561-566

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Continuous cultures of fused cells secreting antibody of predefined specificity

20 September 2017

cites work

1

1 reference

https://api.crossref.org/works/10.1016/0958-1669(95)80093-X

21 May 2024

Man-made antibodies

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Reshaping human antibodies for therapy

21 May 2024

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Physical map of the 3' region of the human immunoglobulin heavy chain locus: clustering of autoantibody-related variable segments in one haplotype

21 May 2024

9

1 reference

https://api.crossref.org/works/10.1016/0958-1669(95)80093-X

The human immunoglobulin kappa locus consists of two copies that are organized in opposite polarity

21 May 2024

10

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https://api.crossref.org/works/10.1016/0958-1669(95)80093-X

The human immunoglobulin VH repertoire

21 May 2024

11

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https://api.crossref.org/works/10.1016/0958-1669(95)80093-X

Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs

21 May 2024

13

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https://api.crossref.org/works/10.1016/0958-1669(95)80093-X

Preparation of clone libraries in yeast artificial-chromosome vectors

21 May 2024

14

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Germ-line transmission and expression of a human-derived yeast artificial chromosome

21 May 2024

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https://api.crossref.org/works/10.1016/0958-1669(95)80093-X

Analysis of the structural integrity of YACs comprising human immunoglobulin genes in yeast and in embryonic stem cells

21 May 2024

16

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Analysis of homozygous mutant chimeric mice: deletion of the immunoglobulin heavy-chain joining region blocks B-cell development and antibody production

21 May 2024

17

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https://api.crossref.org/works/10.1016/0958-1669(95)80093-X

A repertoire of monoclonal antibodies with human heavy chains from transgenic mice

21 May 2024

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The diversity of antigen-specific monoclonal antibodies from transgenic mice bearing human immunoglobulin gene miniloci

21 May 2024

19

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https://api.crossref.org/works/10.1016/0958-1669(95)80093-X

A transgenic mouse that expresses a diversity of human sequence heavy and light chain immunoglobulins

21 May 2024

20

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https://api.crossref.org/works/10.1016/0958-1669(95)80093-X

Antigen-specific human antibodies from mice comprising four distinct genetic modifications

21 May 2024

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https://api.crossref.org/works/10.1016/0958-1669(95)80093-X

Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes

21 May 2024

22

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https://api.crossref.org/works/10.1016/0958-1669(95)80093-X

Human immunoglobulin transgenes undergo rearrangement, somatic mutation and class switching in mice that lack endogenous IgM.

21 May 2024

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Human immunoglobulin heavy-chain minilocus recombination in transgenic mice: gene-segment use in mu and gamma transcripts

21 May 2024

24

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https://api.crossref.org/works/10.1016/0958-1669(95)80093-X

21 May 2024

Identifiers

1 reference

20 September 2017

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