Development of an inducible suicide gene system based on human caspase 8. (Q40450767)

20 September 2017

title

Development of an inducible suicide gene system based on human caspase 8. (English)

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20 September 2017

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Françoise Carlotti

1

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Rob C Hoeben

object named as

Rob C Hoeben

5

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author name string

Arnaud Zaldumbide

2

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20 September 2017

Patrick Martin

3

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20 September 2017

Kim E Boulukos

4

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20 September 2017

Philippe Pognonec

6

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20 September 2017

publication date

1 July 2005

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20 September 2017

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20 September 2017

volume

12

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20 September 2017

issue

7

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20 September 2017

page(s)

627-639

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Influence of the bystander effect on HSV-tk/GCV gene therapy. A review

20 September 2017

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Ganciclovir nucleotides accumulate in mitochondria of rat liver cells expressing the herpes simplex virus thymidine kinase gene

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Ganciclovir chemoablation of herpes thymidine kinase suicide gene-modified tumors produces tumor necrosis and induces systemic immune responses

21 January 2018

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A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease

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Suicide gene therapy mediated by the Herpes Simplex virus thymidine kinase gene/Ganciclovir system: fifteen years of application.

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Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal

21 January 2018

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Controlling mammalian gene expression with small molecules

21 January 2018

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Controlling Signal Transduction with Synthetic Ligands

21 January 2018

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Functional analysis of Fas signaling in vivo using synthetic inducers of dimerization

21 January 2018

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Synthetic activation of caspases: artificial death switches

21 January 2018

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An induced proximity model for caspase-8 activation.

21 January 2018

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Autoproteolytic activation of pro-caspases by oligomerization

21 January 2018

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Redesigning an FKBP-ligand interface to generate chemical dimerizers with novel specificity

21 January 2018

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Transcriptional activation by tetracyclines in mammalian cells

21 January 2018

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Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

21 January 2018

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Lentiviral vectors efficiently transduce quiescent mature 3T3-L1 adipocytes

21 January 2018

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Development of multigene and regulated lentivirus vectors

21 January 2018

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Apoptosis induced by microinjection of cytochrome c is caspase-dependent and is inhibited by Bcl-2.

21 January 2018

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FasL induces Fas/Apo1-mediated apoptosis in human embryonic kidney 293 cells routinely used to generate E1-deleted adenoviral vectors.

21 January 2018

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Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

21 January 2018

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Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32.

21 January 2018

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Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB.

21 January 2018

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Caspase involvement in RIP-associated CD95-induced T cell apoptosis

21 January 2018

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Photodynamic therapy of human breast cancer xenografts lacking caspase-3.

21 January 2018

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Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

21 January 2018

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Death receptors: signaling and modulation

21 January 2018

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Caspases: key players in programmed cell death

21 January 2018

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Caspase activation: the induced-proximity model

21 January 2018

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Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme

21 January 2018

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Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35.

21 January 2018

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Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex

21 January 2018

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Inhibition of death receptor signals by cellular FLIP

21 January 2018

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c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis

21 January 2018

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The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex

21 January 2018

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21 January 2018

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21 January 2018

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A tetracycline controlled activation/repression system with increased potential for gene transfer into mammalian cells

21 January 2018

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Stringent control of gene expression in vivo by using novel doxycycline-dependent trans-activators

21 January 2018

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Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

21 January 2018

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Gene transfer of a chimeric trans-activator is immunogenic and results in short-lived transgene expression

21 January 2018

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A unified model for apical caspase activation

21 January 2018

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Interdimer processing mechanism of procaspase-8 activation.

21 January 2018

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A mechanistic role for cardiac myocyte apoptosis in heart failure

21 January 2018

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Conditional cell ablation by tight control of caspase-3 dimerization in transgenic mice.

21 January 2018

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A third-generation lentivirus vector with a conditional packaging system

21 January 2018

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7 January 2021

Development of a self-inactivating lentivirus vector.

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7 January 2021

Lentivirus Vectors Encoding Both Central Polypurine Tract and Posttranscriptional Regulatory Element Provide Enhanced Transduction and Transgene Expression

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7 January 2021

Inhibition of fas death signals by FLIPs

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7 January 2021

Identifiers

DOI

10.1038/SJ.CGT.7700825

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Dimensions Publication ID

20 September 2017

1014614610

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