Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells. (Q40462629)

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8 January 2020

title

Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells (English)

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8 January 2020

7

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Silvia Fernández de Mattos

8 January 2020

2

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8 January 2020

Inês Soeiro

4

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8 January 2020

Eric W-F Lam

8

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8 January 2020

author name string

Abdelkader Essafi

1

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8 January 2020

Yasmin A M Hassen

3

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8 January 2020

Ghulam J Mufti

5

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8 January 2020

N Shaun B Thomas

6

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8 January 2020

language of work or name

English

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publication date

1 March 2005

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8 January 2020

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8 January 2020

volume

24

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8 January 2020

issue

14

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8 January 2020

page(s)

2317-2329

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A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

8 January 2020

cites work

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FOXO transcription factors as regulators of immune homeostasis: molecules to die for?

21 January 2018

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Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein Bim and suppresses its proapoptotic activity by phosphorylation

21 January 2018

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Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty

21 January 2018

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FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity

21 January 2018

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The biology of chronic myeloid leukemia

21 January 2018

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Cytokines and BCR-ABL mediate suppression of TRAIL-induced apoptosis through inhibition of forkhead FOXO3a transcription factor

21 January 2018

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FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

21 January 2018

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A member of Forkhead transcription factor FKHRL1 is a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells

21 January 2018

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Signalling through phosphoinositide 3-kinases: the lipids take centre stage

21 January 2018

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Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

21 January 2018

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Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover

21 January 2018

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The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity

21 January 2018

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The Akt pathway: molecular targets for anti-cancer drug development

21 January 2018

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BCR-ABL and interleukin 3 promote haematopoietic cell proliferation and survival through modulation of cyclin D2 and p27Kip1 expression.

21 January 2018

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The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

21 January 2018

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FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines

21 January 2018

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The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor

21 January 2018

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P230 BCR/ABL protein may be associated with an acute leukaemia phenotype

21 January 2018

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BCR signals target p27Kip1 and cyclin D2 via the PI3-K signalling pathway to mediate cell cycle arrest and apoptosis of WEHI 231 B cells

21 January 2018

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7 January 2021

A system for stable expression of short interfering RNAs in mammalian cells

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7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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7 January 2021

A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia positive acute lymphoblastic leukaemia

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7 January 2021

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

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7 January 2021

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

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7 January 2021

Roles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors

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7 January 2021

Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208421

7 January 2021

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

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7 January 2021

FLT3 receptors with internal tandem duplications promote cell viability and proliferation by signaling through Foxo proteins

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7 January 2021

Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208421

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15688014%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

8 January 2020

1020124707

0 references

1 reference