Simultaneous inhibition of epidermal growth factor receptor (EGFR) signaling and enhanced activation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-mediated apoptosis induction by an scFv:sTRAIL fusion protein with speci (Q40472879)

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English	Simultaneous inhibition of epidermal growth factor receptor (EGFR) signaling and enhanced activation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-mediated apoptosis induction by an scFv:sTRAIL fusion protein with speci	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

20 September 2017

Simultaneous inhibition of epidermal growth factor receptor (EGFR) signaling and enhanced activation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-mediated apoptosis induction by an scFv:sTRAIL fusion protein with speci (English)

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Europe PubMed Central

PubMed publication ID

20 September 2017

apoptotic process

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1

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Europe PubMed Central

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20 September 2017

Wijnand Helfrich

7

object named as

Wijnand Helfrich

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20 September 2017

author name string

Douwe F Samplonius

2

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Europe PubMed Central

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20 September 2017

Linda van Genne

3

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20 September 2017

Marike H Dijkstra

4

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20 September 2017

Bart Jan Kroesen

5

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Europe PubMed Central

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20 September 2017

Lou F M H de Leij

6

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20 September 2017

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publication date

11 January 2005

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20 September 2017

Journal of Biological Chemistry

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20 September 2017

280

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Europe PubMed Central

PubMed publication ID

20 September 2017

11

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Europe PubMed Central

PubMed publication ID

20 September 2017

10025-10033

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Europe PubMed Central

PubMed publication ID

20 September 2017

1 reference

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The ErbB receptors and their role in cancer progression.

1 reference

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The ErbB signaling network: receptor heterodimerization in development and cancer

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Untangling the ErbB signalling network

1 reference

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Structural alterations of the epidermal growth factor receptor gene in human gliomas

1 reference

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

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Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs): simple drugs with a complex mechanism of action?

1 reference

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Studies leading to the identification of ZD1839 (IRESSA): an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer

1 reference

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ZD1839, a selective epidermal growth factor receptor tyrosine kinase inhibitor, alone and in combination with radiation and chemotherapy as a new therapeutic strategy in non-small cell lung cancer

1 reference

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21 January 2018

Pemetrexed: single-agent and combination phase I study overview

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EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Epidermal growth factor receptor

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21 January 2018

Regulation of Akt by EGF-R inhibitors, a possible mechanism of EGF-R inhibitor-enhanced TRAIL-induced apoptosis

1 reference

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21 January 2018

Identification and characterization of a new member of the TNF family that induces apoptosis

1 reference

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21 January 2018

The receptor for the cytotoxic ligand TRAIL

1 reference

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21 January 2018

An antagonist decoy receptor and a death domain-containing receptor for TRAIL

1 reference

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21 January 2018

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

1 reference

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21 January 2018

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413673200

21 January 2018

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413673200

21 January 2018

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413673200

21 January 2018

Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

1 reference

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21 January 2018

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413673200

21 January 2018

Caspase-10 is an initiator caspase in death receptor signaling

1 reference

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21 January 2018

Safety and antitumor activity of recombinant soluble Apo2 ligand

1 reference

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21 January 2018

Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity.

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21 January 2018

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

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Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) triggers apoptosis in normal prostate epithelial cells

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21 January 2018

Target cell-restricted and -enhanced apoptosis induction by a scFv:sTRAIL fusion protein with specificity for the pancarcinoma-associated antigen EGP2.

1 reference

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21 January 2018

Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor

1 reference

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21 January 2018

Dimeric and trimeric antibodies: high avidity scFvs for cancer targeting.

1 reference

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21 January 2018

c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis

1 reference

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21 January 2018

Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

1 reference

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Phosphatidylinositol 3-kinase/Akt signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP).

1 reference

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21 January 2018

Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias

1 reference

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Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45

1 reference

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21 January 2018

MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors

1 reference

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21 January 2018

Exceptionally potent anti-tumor bystander activity of an scFv:sTRAIL fusion protein with specificity for EGP2 toward target antigen-negative tumor cells

1 reference

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21 January 2018

Combined epidermal growth factor receptor targeting with the tyrosine kinase inhibitor gefitinib (ZD1839) and the monoclonal antibody cetuximab (IMC-C225): superiority over single-agent receptor targeting.

1 reference

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21 January 2018

Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)

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A dimeric bispecific miniantibody combines two specificities with avidity

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21 January 2018

Identifiers

10.1074/JBC.M413673200

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

ResearchGate publication ID

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