Secreted protein acidic, rich in cysteine (SPARC), mediates cellular survival of gliomas through AKT activation (Q40506981)

21 September 2017

title

Secreted protein acidic, rich in cysteine (SPARC), mediates cellular survival of gliomas through AKT activation (English)

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21 September 2017

5

Henry S Friedman

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21 September 2017

6

Darell D Bigner

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21 September 2017

8

Jeremy N Rich

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21 September 2017

Qing Shi

1

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21 September 2017

Shideng Bao

2

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21 September 2017

Jill A Maxwell

3

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21 September 2017

Elizabeth D Reese

4

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21 September 2017

Xiao-Fan Wang

7

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21 September 2017

language of work or name

English

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publication date

5 October 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

279

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21 September 2017

issue

50

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21 September 2017

page(s)

52200-52209

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Validation and predictive power of Radiation Therapy Oncology Group (RTOG) recursive partitioning analysis classes for malignant glioma patients: a report using RTOG 90-06.

21 September 2017

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SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury

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Distribution of the calcium-binding protein SPARC in tissues of embryonic and adult mice.

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SPARC mediates focal adhesion disassembly in endothelial cells through a follistatin-like region and the Ca(2+)-binding EF-hand.

21 January 2018

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SPARC: a signal of astrocytic neoplastic transformation and reactive response in human primary and xenograft gliomas

21 January 2018

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Identifying potential tumor markers and antigens by database mining and rapid expression screening

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Cost of Migration: Invasion of Malignant Gliomas and Implications for Treatment

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Increased SPARC expression promotes U87 glioblastoma invasion in vitro

21 January 2018

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Development of UV-induced squamous cell carcinomas is suppressed in the absence of SPARC.

21 January 2018

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SPARC affects glioma cell growth differently when grown on brain ECM proteins in vitro under standard versus reduced-serum stress conditions

21 January 2018

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Expression and purification of recombinant human SPARC produced by baculovirus

21 January 2018

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Functional analysis of the matricellular protein SPARC with novel monoclonal antibodies

21 January 2018

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Nonparametric Estimation from Incomplete Observations

21 January 2018

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The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

21 January 2018

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Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

21 January 2018

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Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

21 January 2018

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Association of increased phosphatidylinositol 3-kinase signaling with increased invasiveness and gelatinase activity in malignant gliomas

21 January 2018

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Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production

21 January 2018

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Caspase activation - stepping on the gas or releasing the brakes? Lessons from humans and flies

21 January 2018

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SPARC Inhibits Epithelial Cell Proliferation in Part through Stimulation of the Transforming Growth Factor-β–Signaling System

21 January 2018

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Structural variability of BM-40/SPARC/osteonectin glycosylation: implications for collagen affinity

21 January 2018

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Prognostic significance of an apoptotic index and apoptosis/proliferation ratio for patients with high-grade astrocytomas

21 January 2018

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Imbalance between apostain expression and proliferative index can predict survival in primary glioblastoma

21 January 2018

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Analysis of proliferation and apoptosis in brain gliomas: prognostic and clinical value

21 January 2018

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The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas

21 January 2018

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Growth inhibition of human malignant glioma cells induced by the PI3-K-specific inhibitor

21 January 2018

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Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt.

21 January 2018

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

21 January 2018

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Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis

21 January 2018

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Molecular pathway for cancer metastasis to bone

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M409630200

1 reference

21 September 2017

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