Identification of the Antineoplastic Agent 6-Mercaptopurine as an Activator of the Orphan Nuclear Hormone Receptor Nurr1 (Q40653038)

22 September 2017

title

Identification of the Antineoplastic Agent 6-Mercaptopurine as an Activator of the Orphan Nuclear Hormone Receptor Nurr1 (English)

1 reference

https://api.crossref.org/works/10.1074/JBC.M302167200

26 December 2023

1 reference

1 reference

https://api.crossref.org/works/10.1074/JBC.M302167200

26 December 2023

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https://api.crossref.org/works/10.1074/JBC.M302167200

26 December 2023

author name string

Peter Ordentlich

1

1 reference

22 September 2017

Yingzhuo Yan

2

1 reference

22 September 2017

Sihong Zhou

3

1 reference

22 September 2017

Richard A. Heyman

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12709433

26 December 2023

language of work or name

English

0 references

publication date

22 April 2003

1 reference

full work available at URL

22 September 2017

http://www.jbc.org/article/S0021925820869373/pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12709433

https://api.elsevier.com/content/article/PII:S0021925820869373?httpAccept=text/xml

26 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M302167200

https://api.elsevier.com/content/article/PII:S0021925820869373?httpAccept=text/plain

26 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M302167200

https://syndication.highwire.org/content/doi/10.1074/jbc.M302167200

26 December 2023

1 reference

https://api.crossref.org/works/10.1074/JBC.M302167200

Journal of Biological Chemistry

26 December 2023

published in

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22 September 2017

volume

278

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22 September 2017

issue

27

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22 September 2017

page(s)

24791-24799

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Studies on Condensed Pyrimidine Systems. IX. The Synthesis of Some 6-Substituted Purines

22 September 2017

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6‐Methylmercaptopurine Riboside Is a Potent and Selective Inhibitor of Nerve Growth Factor‐Activated Protein Kinase N

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Association of a purine-analogue-sensitive protein kinase activity with p75 nerve growth factor receptors

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Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis

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Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

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Novel dimeric Nur77 signaling mechanism in endocrine and lymphoid cells

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Antagonism between Nur77 and glucocorticoid receptor for control of transcription.

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Involvement of the nuclear orphan receptor NURR1 in the regulation of corticotropin-releasing hormone expression and actions in human inflammatory arthritis

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LXR, a nuclear receptor that defines a distinct retinoid response pathway

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Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors

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Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation

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Akt phosphorylates and regulates the orphan nuclear receptor Nur77

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Akt inhibits the orphan nuclear receptor Nur77 and T-cell apoptosis

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Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

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Axon Outgrowth Is Regulated by an Intracellular Purine-sensitive Mechanism in Retinal Ganglion Cells

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Identifiers

1 reference

22 September 2017

1 reference