Neprilysin gene transfer reduces human amyloid pathology in transgenic mice. (Q40661439)

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scientific article published on March 2003

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English	Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.	scientific article published on March 2003

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PubMed publication ID

12657655

retrieved

22 September 2017

title

Neprilysin gene transfer reduces human amyloid pathology in transgenic mice (English)

1 reference

stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

main subject

Membrane metalloendopeptidase

1 reference

stated in

GOA release 2020-03-11

amyloid-beta clearance

1 reference

stated in

GOA release 2020-03-11

author

Robert A. Marr

series ordinal

1

object named as

Robert A Marr

2 references

stated in

Europe PubMed Central

PubMed publication ID

12657655

retrieved

22 September 2017

stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

Edward Rockenstein

series ordinal

2

object named as

Edward Rockenstein

2 references

stated in

Europe PubMed Central

PubMed publication ID

12657655

retrieved

22 September 2017

stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

Fred Gage

series ordinal

6

object named as

Fred H Gage

1 reference

stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

Eliezer Masliah

series ordinal

8

object named as

Eliezer Masliah

2 references

PubMed publication ID

12657655

PMC publication ID

6742010

author name string

Atish Mukherjee

series ordinal

3

1 reference

stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

Mark S Kindy

series ordinal

4

1 reference

stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

Louis B Hersh

series ordinal

5

1 reference

stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

Inder M Verma

series ordinal

7

1 reference

stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

language of work or name

English

0 references

publication date

1 March 2003

1 reference

stated in

Europe PubMed Central

PubMed publication ID

12657655

retrieved

22 September 2017

published in

Journal of Neuroscience

1 reference

stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

volume

23

1 reference

stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

issue

6

1 reference

stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

page(s)

1992-1996

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stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

cites work

Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does Alzheimer disease tilt the scales of amyloid degradation versus accumulation?

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced neprilysin in high plaque areas of Alzheimer brain: a possible relationship to deficient degradation of beta-amyloid peptide

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neprilysin (NEP) family of zinc metalloendopeptidases: genomics and function

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neprilysin content is reduced in Alzheimer brain areas

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic regulation of brain Abeta by neprilysin

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical localization of neprilysin in the human cerebral cortex: inverse association with vulnerability to amyloid beta-protein (Abeta) deposition

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between beta amyloid peptide generating molecules and neprilysin in Alzheimer disease and normal brain

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clearance of extracellular and cell-associated amyloid beta peptide through viral expression of neprilysin in primary neurons

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42).

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of association of neprilysin polymorphism with Alzheimer's disease and Alzheimer's disease-type neuropathological changes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dinucleotide repeat polymorphisms in the neprilysin gene are not associated with sporadic Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta 42-induced increase in neprilysin is associated with prevention of amyloid plaque formation in vivo

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-fibril formation. Proposed mechanisms and relevance to conformational disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

16 Neprilysin: Assay methods, purification, and characterization

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation and culturing of precursor cells and neuroblasts from embryonic and adult central nervous system

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of a self-inactivating lentivirus vector.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A third-generation lentivirus vector with a conditional packaging system

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/12657655

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1523/JNEUROSCI.23-06-01992.2003

1 reference

stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

PMC publication ID

6742010

1 reference

stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

PubMed publication ID

12657655

1 reference

stated in

Europe PubMed Central

PMC publication ID

6742010

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742010&resulttype=core&format=json

retrieved

12 May 2020

 

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