Functional correction of episomal mutations with short DNA fragments and RNA-DNA oligonucleotides. (Q40740212)

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8 December 2019

title

Functional correction of episomal mutations with short DNA fragments and RNA-DNA oligonucleotides (English)

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8 December 2019

1

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8 December 2019

David J. Porteous

series ordinal

3

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8 December 2019

author name string

B J Stevenson

series ordinal

2

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8 December 2019

publication date

1 March 2002

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8 December 2019

published in

Journal of Gene Medicine

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8 December 2019

volume

4

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issue

2

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8 December 2019

page(s)

195-204

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Altering the genome by homologous recombination

8 December 2019

cites work

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Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination

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Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene.

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Efficient gene targeting in mouse embryonic stem cells

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Gene targeting for gene therapy: prospects

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Gene correction in hematopoietic progenitor cells by homologous recombination

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Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell

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Targeted replacement of normal and mutant CFTR sequences in human airway epithelial cells using DNA fragments

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Targeted correction of a defective selectable marker gene in human epithelial cells by small DNA fragments

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Expression of DeltaF508 CFTR in normal mouse lung after site-specific modification of CFTR sequences by SFHR.

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The REC2 gene encodes the homologous pairing protein of Ustilago maydis

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Targeted gene repair directed by the chimeric RNA/DNA oligonucleotide in a mammalian cell-free extract

21 January 2018

1 reference

Targeted gene correction of episomal DNA in mammalian cells mediated by a chimeric RNA.DNA oligonucleotide

21 January 2018

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Rescue of dystrophin expression in mdx mouse muscle by RNA/DNA oligonucleotides

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The potential of nucleic acid repair in functional genomics

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SV40-transformed simian cells support the replication of early SV40 mutants

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A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells

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Gene targeting is enhanced in human cells overexpressing hRAD51.

21 January 2018

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A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

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Influence of DNA delivery method on gene targeting frequencies in human cells

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Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

21 January 2018

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A sequence-specific gene correction by an RNA-DNA oligonucleotide in mammalian cells characterized by transfection and nuclear extract using a lacZ shuttle system

21 January 2018

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Gene correction of the apolipoprotein (Apo) E2 phenotype to wild-type ApoE3 by in situ chimeraplasty

21 January 2018

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Targeted gene correction by small single-stranded oligonucleotides in mammalian cells

21 January 2018

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Different frequency of gene targeting events by the RNA-DNA oligonucleotide among epithelial cells

21 January 2018

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Homologous recombination based gene therapy

21 January 2018

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In vivo and in vitro correction of the mdx dystrophin gene nonsense mutation by short-fragment homologous replacement

21 January 2018

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Targeted nucleotide exchange in the alkaline phosphatase gene of HuH-7 cells mediated by a chimeric RNA/DNA oligonucleotide

21 January 2018

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In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides

21 January 2018

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Persistent failures in gene repair

21 January 2018

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Gene repair validation

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21 January 2018

Identifiers

DOI

10.1002/JGM.249

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8 December 2019

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