Inhibitors of collagenase but not of gelatinase reduce cartilage explant proteoglycan breakdown despite only low levels of matrix metalloproteinase activity (Q40849569)

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English	Inhibitors of collagenase but not of gelatinase reduce cartilage explant proteoglycan breakdown despite only low levels of matrix metalloproteinase activity	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

Inhibitors of collagenase but not of gelatinase reduce cartilage explant proteoglycan breakdown despite only low levels of matrix metalloproteinase activity (English)

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

1 reference

based on heuristic

inferred from title

author name string

Brown CJ

1

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

Rahman S

2

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

Morton AC

3

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

Beauchamp CL

4

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

Bramwell H

5

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

Buttle DJ

6

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

publication date

1 December 1996

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Europe PubMed Central

PMC publication ID

24 September 2017

Clinical Molecular Pathology

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

49

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

6

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

M331-9

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

Chondrocyte matrix metalloproteinase-8. Human articular chondrocytes express neutrophil collagenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

Biochemical characterization of human collagenase-3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the 'metzincins'

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

Fibroblast and neutrophil collagenases cleave at two sites in the cartilage aggrecan interglobular domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

Structural interaction of natural and synthetic inhibitors with the venom metalloproteinase, atrolysin C (form d)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

Neutrophil collagenase (MMP-8) cleaves at the aggrecanase site E373-A374 in the interglobular domain of cartilage aggrecan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

Evolutionary families of metallopeptidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

Human cathepsin B1. Purification and some properties of the enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

Purification of cathepsin B by a new form of affinity chromatography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

Cleavage of cartilage proteoglycan between G1 and G2 domains by stromelysins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

The interglobular domain of cartilage aggrecan is cleaved by PUMP, gelatinases, and cathepsin B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

A rapid and reproducible assay for collagenase using [1-14C]acetylated collagen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

Participation of monocyte-macrophages and lymphocytes in the production of a factor that stimulates collagenase and prostaglandin release by rheumatoid synovial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

Neutral metallo-proteinases of rabbit bone. Separation in latent forms of distinct enzymes that when activated degrade collagen, gelatin and proteoglycans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

24 September 2017

Blocking cartilage destruction with metalloproteinase inhibitors: a valid therapeutic target?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

25 September 2017

Nitric oxide and energy production in articular chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

17 June 2018

Purification of rabbit bone inhibitor of collagenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

17 June 2018

Articular cartilage cultured with catabolin (pig interleukin 1) synthesizes a decreased number of normal proteoglycan molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

17 June 2018

Effect of recombinant cytokines on glycolysis and fructose 2,6-bisphosphate in rheumatoid synovial cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

17 June 2018

Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

17 June 2018

Murine interleukin-1 receptor: differences in binding properties between fibroblastic and thymoma cells and evidence for a two-chain receptor model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

17 June 2018

Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

17 June 2018

Transforming growth factor-beta causes partial inhibition of interleukin 1-stimulated cartilage degradation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

17 June 2018

Inhibition of interleukin 1-stimulated cartilage proteoglycan degradation by a lipophilic inactivator of cysteine endopeptidases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

17 June 2018

Metalloproteinase digestion of cartilage proteoglycan. Pattern of cleavage by stromelysin and susceptibility to collagenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

17 June 2018

Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

17 June 2018

Mechanism of catabolism of aggrecan by articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

17 June 2018

Lysosomal cysteine endopeptidases mediate interleukin 1-stimulated cartilage proteoglycan degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

17 June 2018

4 Assay of proteoglycan degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

19 August 2018

Potent collagenase inhibitors prevent interleukin-1-induced cartilage degradation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=408083

4 November 2018

Studies on the angiotensin converting enzyme with different substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of proteolytic enzymes on the mechanical properties of adult human articular cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of an Asn/Val cleavage site in the production of a soluble form of a human tumor necrosis factor (TNF) receptor. Site-directed mutagenesis of a putative cleavage site in the p55 TNF receptor chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo expression of stromelysin in synovium and cartilage of rabbits injected intraarticularly with interleukin-1 beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synthetic peptide metalloproteinase inhibitor, but not TIMP, prevents the breakdown of proteoglycan within articular cartilage in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discoordinate expression of stromelysin, collagenase, and tissue inhibitor of metalloproteinases-1 in rheumatoid human synovial fibroblasts. Synergistic effects of interleukin-1 and tumor necrosis factor-alpha on stromelysin expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a stromelysin cleavage site within the interglobular domain of human aggrecan. Evidence for proteolysis at this site in vivo in human articular cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of latent and high Mr active forms of stromelysin to collagen is mediated by the C-terminal domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The origin of matrix metalloproteinases and their familial relationships

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catabolism of aggrecan in cartilage explants. Identification of a major cleavage site within the interglobular domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a specific antiserum to rabbit stromelysin and demonstration of the synthesis of collagenase and stromelysin by stimulated rabbit articular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo effects of antirheumatic drugs on neutral collagenolytic proteases in human rheumatoid arthritis cartilage and synovium

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of synthetic metalloprotease inhibitors on cartilage autolysis in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of retinoic acid on proteoglycan biosynthesis in bovine articular cartilage cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cathepsin D in cartilage: the immunohistochemical demonstration of extracellular enzyme in normal and pathological conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

52 Mammalian collagenases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A highly sensitive fluorometric assay for "enkephalinase," a neutral metalloendopeptidase that releases tyrosine-glycine-glycine from enkephalins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

31 Quantification of matrix metalloproteinases in tissue samples

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bafilomycin A1 inhibits IL-1-stimulated proteoglycan degradation by chondrocytes without affecting stromelysin synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure of aggrecan fragments in human synovial fluid. Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin B and an inhibitor of matrix metalloproteinases. Evidence for two converging pathways of chondrocyte-mediated proteoglycan degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibition of interleukin 1-stimulated cartilage proteoglycan degradation by cysteine endopeptidase inactivators

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlations between stiffness and the chemical constituents of cartilage on the human femoral head

1 reference

https://pubmed.ncbi.nlm.nih.gov/16696099

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1136/MP.49.6.M331

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

24 September 2017

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