Rank-order of potencies for inhibition of the secretion of abeta40 and abeta42 suggests that both are generated by a single gamma-secretase (Q40942994)

25 September 2017

title

Rank-order of potencies for inhibition of the secretion of abeta40 and abeta42 suggests that both are generated by a single gamma-secretase (English)

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25 September 2017

Durkin JT

1

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25 September 2017

Murthy S

2

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25 September 2017

Husten EJ

3

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25 September 2017

Trusko SP

4

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25 September 2017

Savage MJ

5

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25 September 2017

Rotella DP

6

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25 September 2017

Greenberg BD

7

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25 September 2017

Siman R

8

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25 September 2017

language of work or name

English

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publication date

1 July 1999

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Journal of Biological Chemistry

25 September 2017

published in

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25 September 2017

volume

274

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25 September 2017

issue

29

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25 September 2017

page(s)

20499-20504

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Therapeutic approaches related to amyloid-beta peptide and Alzheimer's disease

25 September 2017

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21 January 2018

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The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

21 January 2018

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Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.

21 January 2018

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Alzheimer's A beta(1-42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Enhanced release of amyloid beta-protein from codon 670/671 "Swedish" mutant beta-amyloid precursor protein occurs in both secretory and endocytic pathways

21 January 2018

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Mutations in the transmembrane domain of APP altering gamma-secretase specificity

21 January 2018

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Preferential adsorption, internalization and resistance to degradation of the major isoform of the Alzheimer's amyloid peptide, A beta 1-42, in differentiated PC12 cells

21 January 2018

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Synthesis of a new cell penetrating calpain inhibitor (calpeptin)

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.29.20499

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25 September 2017

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