Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility (Q41132503)

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scientific article published on January 1997

Language	Label	Description	Also known as
English	Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility	scientific article published on January 1997

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

27 September 2017

Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 September 2017

G protein-coupled receptor

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1

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27 September 2017

6

object named as

B K Kobilka

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Europe PubMed Central

PubMed publication ID

27 September 2017

author name string

J A Ballesteros

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27 September 2017

R Seifert

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27 September 2017

E Sanders-Bush

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27 September 2017

H Weinstein

5

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27 September 2017

language of work or name

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publication date

1 January 1997

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27 September 2017

Journal of Biological Chemistry

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27 September 2017

272

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27 September 2017

5

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27 September 2017

2587-2590

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27 September 2017

G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-adrenergic receptor enhances mitogenesis and tumorigenicity

1 reference

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Constitutively active mutants of rhodopsin

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Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.

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Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas

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A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty

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Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness

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Thrombin receptor activating mutations. Alteration of an extracellular agonist recognition domain causes constitutive signaling

1 reference

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Amino acid side chains that define muscarinic receptor/G-protein coupling. Studies of the third intracellular loop

1 reference

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21 January 2018

Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

1 reference

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Differential transcriptional activation in vitro by NF-kappa B/Rel proteins

1 reference

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21 January 2018

Amino and carboxyl terminal modifications to facilitate the production and purification of a G protein-coupled receptor

1 reference

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Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor

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Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins

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Reverse intrinsic activity of antagonists on G protein-coupled receptors

1 reference

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21 January 2018

The two-state model of receptor activation

1 reference

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21 January 2018

Ligand-induced domain motion in the activation mechanism of a G-protein-coupled receptor.

1 reference

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Rapid GDP release from Gs alpha in patients with gain and loss of endocrine function

1 reference

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Signal transduction by a 5-HT2 receptor: a mechanistic hypothesis from molecular dynamics simulations of the three-dimensional model of the receptor complexed to ligands

1 reference

11 October 2022

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On the definition of efficacy

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.272.5.2587

Turned on to ill effect

1 reference

11 October 2022

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Fluorescence assays for G-protein interactions

1 reference

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Fluorescent labeling of purified beta 2 adrenergic receptor. Evidence for ligand-specific conformational changes

1 reference

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Identifiers

10.1074/JBC.272.5.2587

1 reference

Europe PubMed Central

PubMed publication ID

27 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 September 2017

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