AMPA receptor flip/flop mutants affecting deactivation, desensitization, and modulation by cyclothiazide, aniracetam, and thiocyanate. (Q41157007)

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scientific article published on November 1996

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English	AMPA receptor flip/flop mutants affecting deactivation, desensitization, and modulation by cyclothiazide, aniracetam, and thiocyanate.	scientific article published on November 1996

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scholarly article

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Europe PubMed Central

PubMed publication ID

8824304

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8824304%20AND%20SRC:MED&resulttype=core&format=json

retrieved

19 October 2019

title

AMPA receptor flip/flop mutants affecting deactivation, desensitization, and modulation by cyclothiazide, aniracetam, and thiocyanate (English)

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PubMed publication ID

8824304

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8824304%20AND%20SRC:MED&resulttype=core&format=json

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19 October 2019

main subject

desensitization

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author name string

K M Partin

series ordinal

1

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Europe PubMed Central

PMC publication ID

6579261

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579261&resulttype=core&format=json

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15 May 2020

M W Fleck

series ordinal

2

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PMC publication ID

6579261

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579261&resulttype=core&format=json

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15 May 2020

M L Mayer

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3

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PMC publication ID

6579261

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15 May 2020

language of work or name

English

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publication date

1 November 1996

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Europe PubMed Central

PubMed publication ID

8824304

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8824304%20AND%20SRC:MED&resulttype=core&format=json

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19 October 2019

published in

Journal of Neuroscience

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Europe PubMed Central

PMC publication ID

6579261

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15 May 2020

volume

16

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Europe PubMed Central

PMC publication ID

6579261

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15 May 2020

issue

21

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Europe PubMed Central

PMC publication ID

6579261

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15 May 2020

page(s)

6634-6647

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PMC publication ID

6579261

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15 May 2020

cites work

Glutamate-operated channels: developmentally early and mature forms arise by alternative splicing

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Structural determinants of allosteric regulation in alternatively spliced AMPA receptors

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Control of kinetic properties of AMPA receptor channels by nuclear RNA editing

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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inferred from PubMed ID database lookup

Interactions among GYKI-52466, cyclothiazide, and aniracetam at recombinant AMPA and kainate receptors.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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inferred from PubMed ID database lookup

Identification of a Ca2+/calmodulin-dependent protein kinase II regulatory phosphorylation site in non-N-methyl-D-aspartate glutamate receptors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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inferred from PubMed ID database lookup

Opening rate of acetylcholine receptor channels

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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inferred from PubMed ID database lookup

Glutamate receptor channels in isolated patches from CA1 and CA3 pyramidal cells of rat hippocampal slices

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 benzothiadiazine S,S-dioxide (IDRA 21): a benzothiadiazine derivative that enhances cognition by attenuating DL-alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (AMPA) receptor desensitization.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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inferred from PubMed ID database lookup

Diazoxide blocks glutamate desensitization and prolongs excitatory postsynaptic currents in rat hippocampal neurons

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A molecular determinant for submillisecond desensitization in glutamate receptors

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPA receptor subunits expressed by single Purkinje cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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inferred from PubMed ID database lookup

Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Effect of thiocyanate on AMPA receptor mediated responses in excised patches and hippocampal slices

1 reference

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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inferred from PubMed ID database lookup

Prolonged presence of glutamate during excitatory synaptic transmission to cerebellar Purkinje cells.

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PubMed

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12 December 2020

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Centrally active modulators of glutamate receptors facilitate the induction of long-term potentiation in vivo

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Thiocyanate ions selectively antagonize AMPA‐evoked responses in Xenopus laevis oocytes microinjected with rat brain mRNA

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

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Action of brief pulses of glutamate on AMPA/kainate receptors in patches from different neurones of rat hippocampal slices

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Cyclothiazide differentially modulates desensitization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor splice variants

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topology profile for a glutamate receptor: three transmembrane domains and a channel-lining reentrant membrane loop

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Currents through single glutamate receptor channels in outside-out patches from rat cerebellar granule cells

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12 December 2020

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Understanding, improving and using green fluorescent proteins

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PubMed

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12 December 2020

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Mechanisms of activation of glutamate receptors and the time course of excitatory synaptic currents.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Facilitation of glutamate receptors enhances memory

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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inferred from PubMed ID database lookup

The kinetics of the response to glutamate and kainate in neurons of the avian cochlear nucleus

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional models of non-NMDA glutamate receptors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of cyclothiazide on binding properties of AMPA-type glutamate receptors: lack of competition between cyclothiazide and GYKI 52466.

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Activation and desensitization of glutamate-activated channels mediating fast excitatory synaptic currents in the visual cortex

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12 December 2020

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inferred from PubMed ID database lookup

A family of AMPA-selective glutamate receptors

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12 December 2020

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High-efficiency transformation of mammalian cells by plasmid DNA

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Molecular dissection of the agonist binding site of an AMPA receptor.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of AMPA/kainate receptors by analogues of diazoxide and cyclothiazide in thin slices of rat hippocampus.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of excitatory synaptic transmission by drugs that reduce desensitization at AMPA/kainate receptors

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Desensitized states prolong GABAA channel responses to brief agonist pulses.

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

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Phosphorylation and regulation of glutamate receptors by calcium/calmodulin-dependent protein kinase II.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allosteric interactions between cyclothiazide and AMPA/kainate receptor antagonists

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic acetylcholine receptor at 9 A resolution.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Benzothiadiazides inhibit rapid glutamate receptor desensitization and enhance glutamatergic synaptic currents.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

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Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS

1 reference

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Negative allosteric modulation of wild-type and mutant AMPA receptors by GYKI 53655

1 reference

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Green fluorescent protein as a marker for gene expression

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteins

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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[3H]aniracetam binds to specific recognition sites in brain membranes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

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Glutamate-activated currents in outside-out patches from spiny versus aspiny hilar neurons of rat hippocampal slices.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloned glutamate receptors

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Bacterial periplasmic transport systems: structure, mechanism, and evolution

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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inferred from PubMed ID database lookup

Calcium-permeable AMPA-kainate receptors in fusiform cerebellar glial cells

1 reference

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS

1 reference

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPA receptor heterogeneity in rat hippocampal neurons revealed by differential sensitivity to cyclothiazide

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Piracetam and other structurally related nootropics

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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A kinetic analysis of the modulation of N-methyl-D-aspartic acid receptors by glycine in mouse cultured hippocampal neurones

1 reference

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate

1 reference

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reference URL

https://pubmed.ncbi.nlm.nih.gov/8824304

retrieved

12 December 2020

based on heuristic

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Modulation of the time course of fast EPSCs and glutamate channel kinetics by aniracetam

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

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Subunit composition at the single-cell level explains functional properties of a glutamate-gated channel

1 reference

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning and functional expression of glutamate receptor subunit genes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclothiazide decreases [3H]AMPA binding to rat brain membranes: evidence that AMPA receptor desensitization increases agonist affinity.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

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Regulation of glycine-insensitive desensitization of the NMDA receptor in outside-out patches

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor desensitization after removal of glutamate

1 reference

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https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

based on heuristic

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Interactions of 2,3-benzodiazepines and cyclothiazide at AMPA receptors: patch clamp recordings in cultured neurones and area CA1 in hippocampal slices

1 reference

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reference URL

https://pubmed.ncbi.nlm.nih.gov/8824304

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of N-methyl-D-aspartic acid receptor desensitization by glycine in mouse cultured hippocampal neurones

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8824304

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aniracetam reduces glutamate receptor desensitization and slows the decay of fast excitatory synaptic currents in the hippocampus

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8824304

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12 December 2020

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Identifiers

DOI

10.1523/JNEUROSCI.16-21-06634.1996

1 reference

stated in

Europe PubMed Central

PMC publication ID

6579261

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579261&resulttype=core&format=json

retrieved

15 May 2020

PMC publication ID

6579261

1 reference

stated in

Europe PubMed Central

PMC publication ID

6579261

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579261&resulttype=core&format=json

retrieved

15 May 2020

PubMed publication ID

8824304

1 reference

stated in

Europe PubMed Central

PMC publication ID

6579261

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6579261&resulttype=core&format=json

retrieved

15 May 2020

 

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