The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity (Q41360894)

29 September 2017

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title

The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity (English)

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29 September 2017

Tedder TF

1

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29 September 2017

Inaoki M

series ordinal

2

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29 September 2017

Sato S

series ordinal

3

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29 September 2017

language of work or name

English

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publication date

1 February 1997

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29 September 2017

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29 September 2017

volume

6

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29 September 2017

issue

2

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29 September 2017

page(s)

107-118

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Structure and function of the complement receptors, CR1 (CD35) and CR2 (CD21).

29 September 2017

cites work

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7 January 2021

Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen.

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7 January 2021

The structure of an alternate form of complement C3 that displays costimulatory growth factor activity for B lymphocytes.

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Tyrosine phosphorylation of CD19 in pre-B and mature B cells

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7 January 2021

Specific binding of Fyn and phosphatidylinositol 3‐kinase to the B cell surface glycoprotein CD19 through their src homology 2 domains

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells

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7 January 2021

Effects of anti-Ig antibodies on the development and differentiation of B cells

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7 January 2021

Antibody response to a T-dependent antigen requires B cell expression of complement receptors

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection.

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Expression cloning of an interferon-inducible 17-kDa membrane protein implicated in the control of cell growth

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

C3d of complement as a molecular adjuvant: bridging innate and acquired immunity

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7 January 2021

Hypothesis. Bound C3 as the second signal for B-cell activation

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7 January 2021

Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

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7 January 2021

The CD19/CR2/TAPA-1 complex of B lymphocytes: linking natural to acquired immunity

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Structural differences between the two human complement C4 isotypes affect the humoral immune response

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Transgenic mice and analysis of B-cell tolerance

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Distinctive developmental origins and specificities of murine CD5+ B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death.

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

B-1 cells are made, not born

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Peritoneal Ly-1 B cells: genetic control, autoantibody production, increased lambda light chain expression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Suppression of the Immune Response by a Soluble Complement Receptor of B Lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

In vivo inhibition of the antibody response by a complement receptor-specific monoclonal antibody.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Immune Response of a Patient with Deficiency of the Fourth Component of Complement and Systemic Lupus Erythematosus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

The development and repertoire of B-1 cells (CD5 B cells)

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Development and function of the early B cell repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Defective B cell development and function in Btk-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Natural murine autoantibodies and conventional antibodies exhibit similar degrees of antigenic cross-reactivity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Co-ligation of mouse complement receptors 1 and 2 with surface IgM rescues splenic B cells and WEHI-231 cells from anti-surface IgM-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Self-renewal of B-1 lymphocytes is dependent on CD19.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Molecular analysis of a human interferon-inducible gene family

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Intersection of the complement and immune systems: a signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Growth control of activated, synchronized murine B cells by the C3d fragment of human complement

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Cell cycle control of activated, synchronized murine B lymphocytes—roles of macrophages and complement C3

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Molecular cloning of the cDNA encoding the Epstein-Barr virus/C3d receptor (complement receptor type 2) of human B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Involvement of B-1 cells in mucosal immunity and autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Clonal deletion of autospecific B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Hyperresponsive B cells in CD22-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Complement dependence of localisation of aggregated IgG in germinal centres

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Role of Complement in Induction of the Allergic Response

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Role of complement in induction of antibody production in vivo. Effect of cobra factor and other C3-reactive agents on thymus-dependent and thymus-independent antibody responses

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Clinical expression of systemic lupus erythematosus in patients with C4A deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Conventional B cells, not B-1 cells, are responsible for producing autoantibodies in lpr mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Inhibition of B cell proliferation with anti-CD19 monoclonal antibodies: anti-CD19 antibodies do not interfere with early signaling events triggered by anti-IgM or interleukin 4.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

The CD19 signal transduction molecule is a response regulator of B-lymphocyte differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

CD5+ B cells in autoimmune disease and lymphoid malignancy

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

SH2 domains recognize specific phosphopeptide sequences

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

The CD19/CD21 signal transduction complex of B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Molecular interactions of complement receptors on B lymphocytes: a CR1/CR2 complex distinct from the CR2/CD19 complex

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

CD19 of B Cells as a Surrogate Kinase Insert Region to Bind Phosphatidylinositol 3-Kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

The CR2/CD19 complex on human B cells contains the src-family kinase Lyn

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Dual antigen recognition by B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Identification of a partial cDNA clone for the C3d/Epstein-Barr virus receptor of human B lymphocytes: homology with the receptor for fragments C3b and C4b of the third and fourth components of complement

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Inhibition of immunological memory and T-independent humoral responses by monoclonal antibodies specific for murine complement receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Activation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

Tissue-specific expression of the human CD19 gene in transgenic mice inhibits antigen-independent B-lymphocyte development.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980418-5

7 January 2021

10.1016/S1074-7613(00)80418-5

Identifiers

DOI

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29 September 2017

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