Structural basis for the regulatory interactions of proapoptotic Par-4. (Q41467308)

1 October 2017

Structural basis for the regulatory interactions of proapoptotic Par-4. (English)

1 reference

Udaya Kumar Tiruttani Subhramanyam

1 October 2017

1

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1 June 2020

Jörg Labahn

4

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1 June 2020

author name string

Jan Kubicek

2

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1 June 2020

Ulf B Eidhoff

3

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1 June 2020

publication date

16 June 2017

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Cell Death & Differentiation

1 October 2017

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1 June 2020

volume

24

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1 June 2020

issue

9

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1 June 2020

page(s)

1540-1547

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Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International

1 June 2020

copyright license

start time

16 June 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Cancer-selective apoptotic effects of extracellular and intracellular Par-4.

11 June 2018

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11 June 2018

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11 June 2018

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Apoptosis and tumor resistance conferred by Par-4

11 June 2018

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QMEAN: A comprehensive scoring function for model quality assessment.

11 June 2018

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11 June 2018

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Regulation of cancer cell survival by Par-4.

11 June 2018

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The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

11 June 2018

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Par-4-mediated recruitment of Amida to the actin cytoskeleton leads to the induction of apoptosis

11 June 2018

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Binding and phosphorylation of par-4 by akt is essential for cancer cell survival.

11 June 2018

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The structure of alpha-helical coiled coils

11 June 2018

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Phosphorylation of Par-4 by protein kinase A is critical for apoptosis

11 June 2018

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Analysis and prediction of leucine-rich nuclear export signals

11 June 2018

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AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4

11 June 2018

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11 June 2018

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Identification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cells

11 June 2018

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Unique stabilizing interactions identified in the two-stranded α-helical coiled-coil: Crystal structure of a cortexillin I/GCN4 hybrid coiled-coil peptide

11 June 2018

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THAP1 is a nuclear proapoptotic factor that links prostate-apoptosis-response-4 (Par-4) to PML nuclear bodies

11 June 2018

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Stabilization of a pH-sensitive apoptosis-linked coiled coil through single point mutations

11 June 2018

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Substructure solution with SHELXD

11 June 2018

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Removing an interhelical salt bridge abolishes coiled-coil formation in a de novo designed peptide

11 June 2018

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Improving coiled-coil stability by optimizing ionic interactions

11 June 2018

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p62 forms a ternary complex with PKCzeta and PAR-4 and antagonizes PAR-4-induced PKCzeta inhibition

11 June 2018

1 reference

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pH-induced folding of an apoptotic coiled coil

11 June 2018

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11 June 2018

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An intrahelical salt bridge within the trigger site stabilizes the GCN4 leucine zipper

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

Interaction partners of Dlk/ZIP kinase: co-expression of Dlk/ZIP kinase and Par-4 results in cytoplasmic retention and apoptosis

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

AATF, a novel transcription factor that interacts with Dlk/ZIP kinase and interferes with apoptosis

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

Evidence that Par-4 participates in the pathogenesis of HIV encephalitis

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

An autonomous folding unit mediates the assembly of two-stranded coiled coils

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

ZIP kinase, a novel serine/threonine kinase which mediates apoptosis

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

Immunohistochemical analysis of the proapoptotic protein Par-4 in normal rat tissues

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

Expression and function of the leucine zipper protein Par-4 in apoptosis

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

Solvent content of protein crystals

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

Predicting coiled coils from protein sequences

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

X-ray scattering indicates that the leucine zipper is a coiled coil

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

Two-state conformational equilibrium in the Par-4 leucine zipper domain.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

Par-4 is an essential downstream target of DAP-like kinase (Dlk) in Dlk/Par-4-mediated apoptosis

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

Intrinsic disorder and coiled-coil formation in prostate apoptosis response factor 4.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5563986

Participation of par-4 in the degeneration of striatal neurons induced by metabolic compromise with 3-nitropropionic acid

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDD.2017.76

7 January 2021

The prostate apoptosis response-4 protein participates in motor neuron degeneration in amyotrophic lateral sclerosis

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDD.2017.76

7 January 2021

https://api.crossref.org/works/10.1038%2FCDD.2017.76

1 reference

7 January 2021

Production of selenomethionine-labelled proteins using simplified culture conditions and generally applicable host/vector systems

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDD.2017.76

7 January 2021

Identifiers

DOI

10.1038/CDD.2017.76

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28622290%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28622290%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

PubMed publication ID

28622290

1 reference