Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands. (Q41612272)

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11 November 2019

title

Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands (English)

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11 November 2019

4

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11 November 2019

author name string

S M Alam

1

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11 November 2019

G M Davies

2

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11 November 2019

C M Lin

3

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11 November 2019

W Nasholds

5

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11 November 2019

S C Jameson

6

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11 November 2019

K A Hogquist

7

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11 November 2019

N R Gascoigne

8

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11 November 2019

P J Travers

9

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11 November 2019

language of work or name

English

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publication date

1 February 1999

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11 November 2019

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11 November 2019

volume

10

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11 November 2019

issue

2

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11 November 2019

page(s)

227-237

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T-cell-receptor affinity and thymocyte positive selection

11 November 2019

cites work

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7 January 2021

CD3 ligation on immature thymocytes generates antagonist-like signals appropriate for CD8 lineage commitment, independently of T cell receptor specificity

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7 January 2021

Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]

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CD8 Expression Allows T Cell Signaling by Monomeric Peptide-MHC Complexes

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Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids

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Evidence for multivalent structure of T-cell antigen receptor complex

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Crystal structure of the V alpha domain of a T cell antigen receptor

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Surface plasmon resonance based methods for measuring the kinetics and binding affinities of biomolecular interactions

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Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

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An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

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CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes

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CD4 augments the response of a T cell to agonist but not to antagonist ligands

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T cell receptor antagonist peptides induce positive selection

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Strong agonist ligands for the T cell receptor do not mediate positive selection of functional CD8+ T cells

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Specificity and flexibility in thymic selection

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Ligands for the T-cell receptor: hard times for avidity models

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Assembly of the TCR/CD3 complex: CD3 epsilon/delta and CD3 epsilon/gamma dimers associate indistinctly with both TCR alpha and TCR beta chains. Evidence for a double TCR heterodimer model

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Real-time competitive kinetic analysis of interactions between low-molecular-weight ligands in solution and surface-immobilized receptors

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7 January 2021

Identification of conserved T cell receptor CDR3 residues contacting known exposed peptide side chains from a major histocompatibility complex class I-bound determinant

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7 January 2021

Essential flexibility in the T-cell recognition of antigen

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CD8 modulation of T-cell antigen receptor–ligand interactions on living cytotoxic T lymphocytes

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7 January 2021

A TCR binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists

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7 January 2021

Variant TCR ligands: new insights into the molecular basis of antigen-dependent signal transduction and T-cell activation

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7 January 2021

Kinetic proofreading in T-cell receptor signal transduction

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7 January 2021

Three-dimensional segregation of supramolecular activation clusters in T cells

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7 January 2021

Immobilization chemistries suitable for use in the BIAcore surface plasmon resonance detector

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7 January 2021

Identification and minimization of nonideal binding effects in BIAcore analysis: ferritin/anti-ferritin Fab' interaction as a model system

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7 January 2021

Aggregation of IgE-receptor complexes on rat basophilic leukemia cells does not change the intrinsic affinity but can alter the kinetics of the ligand-IgE interaction

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7 January 2021

Kinetic discrimination in T-cell activation

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7 January 2021

Ligand-specific oligomerization of T-cell receptor molecules

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7 January 2021

Correlation between the number of T cell receptors required for T cell activation and TCR-ligand affinity

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Kinetics of ligand binding to receptor immobilized in a polymer matrix, as detected with an evanescent wave biosensor. I. A computer simulation of the influence of mass transport

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7 January 2021

Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes

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7 January 2021

Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

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Positive selection of CD4+ T cells by TCR ligation without aggregation even in the absence of MHC.

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Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition

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