The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts. (Q41649459)

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5 December 2019

title

The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts (English)

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5 December 2019

10

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5 December 2019

author name string

T L Burgess

1

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5 December 2019

Y Qian

2

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5 December 2019

S Kaufman

3

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B D Ring

4

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5 December 2019

G Van

5

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5 December 2019

C Capparelli

6

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M Kelley

7

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5 December 2019

H Hsu

8

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W J Boyle

9

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S Hu

11

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D L Lacey

12

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5 December 2019

language of work or name

English

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publication date

1 May 1999

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5 December 2019

number of pages

12

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inferred from page(s)

published in

Journal of Cell Biology

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volume

145

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issue

3

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5 December 2019

page(s)

527-538

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Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

5 December 2019

cites work

1 reference

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OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

6 June 2018

1 reference

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RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis

6 June 2018

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The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptor

6 June 2018

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TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts.

6 June 2018

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Characterization of the intracellular domain of receptor activator of NF-kappaB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-kappab and c-Jun N-terminal kinase

6 June 2018

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osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

6 June 2018

1 reference

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Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

6 June 2018

1 reference

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c-Src is required for stimulation of gelsolin-associated phosphatidylinositol 3-kinase

6 June 2018

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Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

6 June 2018

1 reference

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Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro

6 June 2018

1 reference

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Integrin function in osteoclasts

6 June 2018

1 reference

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A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

6 June 2018

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TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells

6 June 2018

1 reference

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Regulation of osteoclast function

6 June 2018

1 reference

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Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis

6 June 2018

1 reference

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Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

6 June 2018

1 reference

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Molecular aspects of osteoclast function

6 June 2018

1 reference

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Osteopontin stimulates gelsolin-associated phosphoinositide levels and phosphatidylinositol triphosphate-hydroxyl kinase

6 June 2018

1 reference

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Osteoclast function is activated by osteoblastic cells through a mechanism involving cell-to-cell contact

6 June 2018

1 reference

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Stimulation of bone resorption and osteoclast clear zone formation by low pH: a time-course study

6 June 2018

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Macrophage colony-stimulating factor stimulates survival and chemotactic behavior in isolated osteoclasts

6 June 2018

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Spatial organization of microfilaments and vitronectin receptor,αvβ3, in osteoclasts: A study using confocal laser scanning microscopy

6 June 2018

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Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts.

6 June 2018

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The osteoclast clear zone is a specialized cell-extracellular matrix adhesion structure

6 June 2018

1 reference

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Effect of substrate composition on bone resorption by rabbit osteoclasts.

6 June 2018

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Role of osteoblasts in hormonal control of bone resorption—A hypothesis

6 June 2018

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Differentiation-inducing factor purified from conditioned medium of mitogen-treated spleen cell cultures stimulates bone resorption

6 June 2018

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'Calcium-activated' intracellular calcium elevation: a novel mechanism of osteoclast regulation.

6 June 2018

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Organization of osteoclast microfilaments during the attachment to bone surface in vitro.

6 June 2018

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Control of cytosolic free calcium in rat and chicken osteoclasts. The role of extracellular calcium and calcitonin

6 June 2018

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The effects of parathyroid hormone (PTH) and PTH-related peptide on osteoclast resorption of bone slices in vitro: an analysis of pit size and the resorption focus

6 June 2018

1 reference

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Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

6 June 2018

1 reference

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Osteoclast resorption-stimulating activity is associated with the osteoblast cell surface and/or the extracellular matrix

6 June 2018

1 reference

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Isolation of a murine osteoclast colony-stimulating factor

6 June 2018

1 reference

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Clear zone in osteoclast function: role of podosomes in regulation of bone-resorbing activity

6 June 2018

1 reference

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Kinetics of the osteoclast cytoskeleton during the resorption cycle in vitro.

6 June 2018

1 reference

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Modulation of osteoclast differentiation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2185088

Osteoclasts express high levels of pp60c-src in association with intracellular membranes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2185088

Osteoclasts express high levels of p60c-src, preferentially on ruffled border membranes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2185088

Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2185088

Osteoclast recruiting activity in bone matrix.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2185088

Wortmannin, a specific inhibitor of phosphatidylinositol-3 kinase, blocks osteoclastic bone resorption.

18 August 2018

1 reference

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Bone Resorbing Activity in Supernatant Fluid from Cultured Human Peripheral Blood Leukocytes

18 August 2018

1 reference

12 December 2020

Effect of pH on bone resorption by rat osteoclasts in vitro

1 reference

12 December 2020

Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures

1 reference

12 December 2020

Adhesion patterns and cytoskeleton of rabbit osteoclasts on bone slices and glass

1 reference

12 December 2020

Phosphatidylinositol-3 kinase is involved in ruffled border formation in osteoclasts

1 reference

12 December 2020

A novel cytokine with osteoclastopoietic activity

1 reference

12 December 2020

Wortmannin, a potent inhibitor of phosphatidylinositol 3-kinase, inhibits osteoclastic bone resorption in vitro

1 reference

12 December 2020

Engagement of the osteoclast integrin alpha v beta 3 by osteopontin stimulates phosphatidylinositol 3-hydroxyl kinase activity

1 reference

12 December 2020

Chemical and physical properties of the extracellular matrix are required for the actin ring formation in osteoclasts

1 reference

12 December 2020

Phosphatidylinositol 3-kinase association with the osteoclast cytoskeleton, and its involvement in osteoclast attachment and spreading

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.145.3.527

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10225954%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10225954%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

PubMed publication ID

10225954

1 reference