A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice (Q41717349)

7 October 2017

title

A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice (English)

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7 October 2017

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Prusiner SB

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DeArmond SJ

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Cohen FE

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7 October 2017

Kaneko K

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7 October 2017

Ball HL

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7 October 2017

Zhang H

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7 October 2017

Groth D

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7 October 2017

Torchia M

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Tremblay P

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7 October 2017

Safar J

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Baldwin MA

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7 October 2017

language of work or name

English

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publication date

1 January 2000

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Journal of Molecular Biology

7 October 2017

published in

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7 October 2017

volume

295

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7 October 2017

issue

4

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7 October 2017

page(s)

997-1007

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Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro

7 October 2017

cites work

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Prion protein of 106 residues creates an artifical transmission barrier for prion replication in transgenic mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Cell-free formation of protease-resistant prion protein.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Temporary and permanent modifications to a single strain of mouse scrapie on transmission to rats and hamsters

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Prion protein peptides induce alpha-helix to beta-sheet conformational transitions

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Mice devoid of PrP are resistant to scrapie

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

NMR structure of the mouse prion protein domain PrP(121-231)

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Characteristics of a Short Incubation Model of Scrapie in the Golden Hamster

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Analysis of the prion protein gene in thalamic dementia

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Linkage of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease to the prion protein gene

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Secondary structure and dosage of soluble and membrane proteins by attenuated total reflection Fourier-transform infrared spectroscopy on hydrated films

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

A transmembrane form of the prion protein in neurodegenerative disease

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Encephalopathy in mice produced by inoculation with scrapie brain material

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Pathologic conformations of prion proteins

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Inherited prion disease with 144 base pair gene insertion. 1. Genealogical and molecular studies

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Scrapie prions aggregate to form amyloid-like birefringent rods

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Species specificity in the cell-free conversion of prion protein to protease-resistant forms: a model for the scrapie species barrier

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

The genomic identity of different strains of mouse scrapie is expressed in hamsters and preserved on reisolation in mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Measurement of the scrapie agent using an incubation time interval assay

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Transmission of bovine spongiform encephalopathy and scrapie to mice

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Purification and structural studies of a major scrapie prion protein

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Neurotoxicity of a prion protein fragment

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Spontaneous neurodegeneration in transgenic mice with mutant prion protein

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Viral particles are required for infection in neurodegenerative Creutzfeldt-Jakob disease.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

An amber mutation of prion protein in Gerstmann-Sträussler syndrome with mutant PrP plaques

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Eight prion strains have PrP(Sc) molecules with different conformations

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

A kinetic model for amyloid formation in the prion diseases: importance of seeding

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Human TSE disease--viral or protein only?

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Conformational transitions in peptides containing two putative alpha-helices of the prion protein.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Linkage of prion protein and scrapie incubation time genes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Serial transmission in rodents of neurodegeneration from transgenic mice expressing mutant prion protein

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Molecular properties of complexes formed between the prion protein and synthetic peptides

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Does the agent of scrapie replicate without nucleic acid?

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Attempts to restore scrapie prion infectivity after exposure to protein denaturants

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Prion protein gene variation among primates

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

The exceptionally small size of the scrapie agent

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Rapid detection of Creutzfeldt-Jakob disease and scrapie prion proteins

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Comparison of scrapie and transmissible mink encephalopathy in hamsters. II. Clinical signs, pathology, and pathogenesis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Linkage of a prion protein missense variant to Gerstmann-Sträussler syndrome

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Thiocyanate and hydroxyl ions inactivate the scrapie agent

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Scrapie prion liposomes and rods exhibit target sizes of 55,000 Da.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Separation of scrapie prion infectivity from PrP amyloid polymers

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Prion Protein Biology

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Novel proteinaceous infectious particles cause scrapie

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/JMBI.1999.3386

Identifiers

DOI

10.1006/JMBI.1999.3386

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7 October 2017

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