Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin alpha(IIb)beta(3). (Q41724428)

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4 November 2019

title

Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin alpha(IIb)beta(3) (English)

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4 November 2019

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3

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4 November 2019

author name string

W Puzon-McLaughlin

series ordinal

1

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4 November 2019

T Kamata

series ordinal

2

1 reference

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4 November 2019

language of work or name

English

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publication date

1 March 2000

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Journal of Biological Chemistry

4 November 2019

published in

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4 November 2019

volume

275

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4 November 2019

issue

11

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4 November 2019

page(s)

7795-7802

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Cell adhesion in vascular biology. New insights into integrin-ligand interaction

4 November 2019

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Critical residues of integrin alphaIIb subunit for binding of alphaIIbbeta3 (glycoprotein IIb-IIIa) to fibrinogen and ligand-mimetic antibodies (PAC-1, OP-G2, and LJ-CP3).

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Ligand binding to integrin alphaIIbbeta3 is dependent on a MIDAS-like domain in the beta3 subunit

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