The concept of type-1 and type-2 helper T cells and their cytokines in humans (Q41722215)

8 October 2017

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title

The concept of type-1 and type-2 helper T cells and their cytokines in humans (English)

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8 October 2017

Del Prete G

1

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8 October 2017

language of work or name

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1 January 1998

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International Reviews of Immunology

8 October 2017

published in

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8 October 2017

volume

16

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8 October 2017

issue

3-4

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8 October 2017

page(s)

427-455

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TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

8 October 2017

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Biology of human TH1 and TH2 cells

21 January 2018

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Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations

21 January 2018

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Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production

21 January 2018

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21 January 2018

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Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production

21 January 2018

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Helper activity for immunoglobulin synthesis of T helper type 1 (Th1) and Th2 human T cell clones: the help of Th1 clones is limited by their cytolytic capacity

21 January 2018

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Switch of CD8 T cells to noncytolytic CD8-CD4- cells that make TH2 cytokines and help B cells.

21 January 2018

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21 January 2018

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Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles

21 January 2018

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Th2-like CD8+ T cells showing B cell helper function and reduced cytolytic activity in human immunodeficiency virus type 1 infection

21 January 2018

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Interleukin (IL) 4, in the absence of antigen stimulation, induces an anergy-like state in differentiated CD8+ TC1 cells: loss of IL-2 synthesis and autonomous proliferation but retention of cytotoxicity and synthesis of other cytokines.

21 January 2018

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The functional role of CD8+ T helper type 2 cells

21 January 2018

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CD30-mediated signaling promotes the development of human T helper type 2-like T cells

21 January 2018

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CD30 expression by CD8+ T cells producing type 2 helper cytokines. Evidence for large numbers of CD8+CD30+ T cell clones in human immunodeficiency virus infection

21 January 2018

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LAG-3, a novel lymphocyte activation gene closely related to CD4

21 January 2018

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Acquisition of lymphokine-producing phenotype by CD4+ T cells

21 January 2018

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T cell genetic background determines default T helper phenotype development in vitro

21 January 2018

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The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model

21 January 2018

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B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

21 January 2018

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Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion

21 January 2018

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Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

21 January 2018

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Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming

21 January 2018

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The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice

21 January 2018

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IgE receptor-positive non-B/non-T cells dominate the production of interleukin 4 and interleukin 6 in immunized mice

21 January 2018

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Induction of interleukin 4 (IL-4) expression in T helper (Th) cells is not dependent on IL-4 from non-Th cells

21 January 2018

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21 January 2018

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Role of NK1.1+ T cells in a TH2 response and in immunoglobulin E production

21 January 2018

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Lymphokine production by human T cells in disease states

21 January 2018

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Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clones

21 January 2018

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The regulation of immunity to Leishmania major

21 January 2018

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The contrasting roles of CD4+ T cells in intracellular infections in humans: leishmaniasis as an example

21 January 2018

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Cytokine patterns in the pathogenesis of human leishmaniasis

21 January 2018

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The role of interferon-gamma in the treatment of visceral and diffuse cutaneous leishmaniasis

21 January 2018

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Regulation and biological function of helminth-induced cytokine responses

21 January 2018

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Immunoglobulin E and effector cells in schistosomiasis

21 January 2018

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Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection

21 January 2018

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Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni

21 January 2018

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Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology

21 January 2018

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Schistosoma-specific helper T cell clones from subjects resistant to infection by Schistosoma mansoni are Th0/2.

21 January 2018

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Borrelia burgdorferi activates a T helper type 1-like T cell subset in Lyme arthritis

21 January 2018

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Development of a mouse model of Helicobacter pylori infection that mimics human disease

21 January 2018

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Recent developments in "nonspecific" inflammatory bowel disease (first of two parts).

21 January 2018

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Human Th1 and Th2 cells: functional properties, regulation of development and role in autoimmunity

21 January 2018

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The T lymphocyte in experimental allergic encephalomyelitis

21 January 2018

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T helper 1 (Th1) functional phenotype of human myelin basic protein-specific T lymphocytes.

21 January 2018

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Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

21 January 2018

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Association between Tumor Necrosis Factor-α and Disease Progression in Patients with Multiple Sclerosis

21 January 2018

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Cytokines in neuroinflammatory disease: role of myelin autoreactive T cell production of interferon-gamma

21 January 2018

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Identification of thyroid stimulating hormone receptor-specific T cells in Graves' disease thyroid using autoantigen-transfected Epstein-Barr virus-transformed B cell lines.

21 January 2018

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TH2 cells in systemic autoimmunity: insights from allogeneic diseases and chemically-induced autoimmunity

21 January 2018

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Mercuric chloride, a chemical responsible for T helper cell (Th)2-mediated autoimmunity in brown Norway rats, directly triggers T cells to produce interleukin-4

21 January 2018

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Fibrogenic cytokines: the role of immune mediators in the development of scar tissue

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830189809043004

Human fibroblasts synthesize elevated levels of extracellular matrix proteins in response to interleukin 4

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830189809043004

Soluble interleukin-2 receptor, interleukin-2 and interleukin-4 in sera and supernatants from patients with progressive systemic sclerosis

21 January 2018

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Messenger RNA expression of the cytokine gene cluster, interleukin 3 (IL-3), IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809043004

Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809043004

Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189809043004

CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells

21 January 2018

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Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

21 January 2018

1 reference

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10.3109/08830189809043004

21 January 2018

Identifiers

DOI

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